Synonyms: Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-; Fluorescein USP; CI Acid Yellow 73; Soap Yellow; CI 45350
CAS No.: 2321-07-5
Molecular Weight: 332.32
Chemical Formula: C20H12O5
Product Codes: M422
Ingredient CAS No Percent Hazardous --------------------------------------- ------------ ------------ --------- Fluorescein 2321-07-5 100% Yes
Emergency Overview
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WARNING! MAY CAUSE ALLERGIC SKIN OR RESPIRATORY REACTION.
SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 1 - Slight
Flammability Rating: 0 - None
Reactivity Rating: 0 - None
Contact Rating: 1 - Slight
Lab Protective Equip: GOGGLES; LAB COAT; PROPER GLOVES
Storage Color Code: Green (General Storage)
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Potential Health Effects
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Inhalation:
May cause allergic reaction in sensitive individuals.
Ingestion:
May cause allergic reaction in sensitive individuals.
Skin Contact:
May cause allergic reaction in sensitive individuals.
Eye Contact:
May cause allergic reaction in sensitive individuals.
Chronic Exposure:
Chronic exposures may cause allergic reaction.
Aggravation of Pre-existing Conditions:
No information found.
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion:
If large amounts were swallowed, give water to drink and get medical advice.
Skin Contact:
Immediately flush skin with plenty of soap and water. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids occasionally. Get medical attention if irritation persists.
Fire:
Not considered to be a fire hazard.
Explosion:
Not considered to be an explosion hazard.
Fire Extinguishing Media:
Use any means suitable for extinguishing surrounding fire.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Spills: Sweep up and containerize for reclamation or disposal. Vacuuming or wet sweeping may be used to avoid dust dispersal.
Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.
Airborne Exposure Limits:
None established.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn. If oil particles (e.g. lubricants, cutting fluids, glycerine, etc.) are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear protective gloves and clean body-covering clothing.
Eye Protection:
Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.
Appearance:
Yellowish-red to red powder.
Odor:
No information found.
Solubility:
Insoluble in water.
Specific Gravity:
No information found.
pH:
No information found.
% Volatiles by volume @ 21C (70F):
0
Boiling Point:
No information found.
Melting Point:
314 - 316C (597 - 601F) Decomposes.
Vapor Density (Air=1):
No information found.
Vapor Pressure (mm Hg):
No information found.
Evaporation Rate (BuAc=1):
No information found.
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizers.
Conditions to Avoid:
Incompatibles.
No LD50/LC50 information found relating to normal routes of occupational exposure. Investigated as a mutagen.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Fluorescein (2321-07-5) No No None
Environmental Fate:
No information found.
Environmental Toxicity:
No information found.
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.
Not regulated.
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Fluorescein (2321-07-5) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Fluorescein (2321-07-5) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Fluorescein (2321-07-5) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Fluorescein (2321-07-5) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: No Fire: No Pressure: No
Reactivity: No (Pure / Solid)
Australian Hazchem Code: None allocated.
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.
NFPA Ratings: Health: 1 Flammability: 1 Reactivity: 0
Label Hazard Warning:
WARNING! MAY CAUSE ALLERGIC SKIN OR RESPIRATORY REACTION.
Label Precautions:
Do not breathe dust.
Keep container closed.
Use only with adequate ventilation.
Avoid prolonged or repeated contact with skin.
Wash thoroughly after handling.
Label First Aid:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. If large amounts were swallowed, give water to drink and get medical advice. In case of skin contact, immediately flush skin with plenty of soap and water. Remove contaminated clothing and shoes. Wash clothing before reuse. In case of eye contact, immediately flush eyes with plenty of water for at least 15 minutes. In all cases, get medical attention.
Product Use:
Laboratory Reagent.
Revision Information:
No Changes.
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Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)