Material Safety Data Sheet

Acetaldehyde MSDS


Section 1: Chemical Product and Company Identification

Product Name: Acetaldehyde

Catalog Codes: SLA1309

CAS#: 75-07-0

RTECS: AB1925000

TSCA: TSCA 8(b) inventory: Acetaldehyde

CI#: Not applicable.

Synonym: Ethyl Aldehyde; Ethanal; Acetic Aldehyde

Chemical Name: Acetaldehyde

Chemical Formula: CH3CHO


Section 2: Composition and Information on Ingredients


Name CAS # % by Weight

Acetaldehyde 75-07-0 100

Toxicological Data on Ingredients: Acetaldehyde: ORAL (LD50): Acute: 661 mg/kg [Rat.]. 900 mg/kg [Mouse]. DERMAL

(LD50): Acute: 3540 mg/kg [Rabbit]. VAPOR (LC50): Acute: 13300 ppm 4 hours [Rat]. 23000 mg/m 4 hours [Mouse].


Section 3: Hazards Identification

Potential Acute Health Effects:

Hazardous in case of eye contact (irritant), of ingestion, of inhalation (lung irritant). Slightly hazardous in case of

skin contact (irritant, permeator).

Potential Chronic Health Effects:

Hazardous in case of skin contact (irritant).

Slightly hazardous in case of skin contact (sensitizer).

CARCINOGENIC EFFECTS: Classified 2B (Possible for human.) by IARC.

MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/or yeast.



The substance may be toxic to liver.

Repeated or prolonged exposure to the substance can produce target organs damage.



Section 4: First Aid Measures

Eye Contact:

Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes,

keeping eyelids open. Cold water may be used. Get medical attention.

Skin Contact:

In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove

contaminated clothing and shoes. Cold water may be used.Wash clothing before reuse. Thoroughly clean shoes

before reuse. Get medical attention.

Serious Skin Contact: Not available.


If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get

medical attention.

Serious Inhalation:

Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or

waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth

resuscitation. Seek medical attention.


Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an

unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight

clothing such as a collar, tie, belt or waistband.

Serious Ingestion: Not available.


Section 5: Fire and Explosion Data

Flammability of the Product: Flammable.

Auto-Ignition Temperature: 175°C (347°F) (ACGIH, 1996; Lewis, 1996; NFPA, 1994); 185 deg. C (ILO, 1998)

Flash Points:

CLOSED CUP: -38°C (-36.4°F) (Buvardi (1996); Clayton and Clayton, 1993; Lewis, 1996); -38.89 deg. C

(American Conference of Govermental Industrial Hygienests) OPEN CUP: -40°C (-40°F) (Lewis, 1997; ACGIH,

1996 (Cleveland).

Flammable Limits:

LOWER: 4% UPPER: 55% (Clayton; Patty's Industrial Hygiene and Toxicology); 57% (American Conference of

Govermental Industrial Hygiensts); 60% (National Fire Protection Association)

Products of Combustion: These products are carbon oxides (CO, CO2).

Fire Hazards in Presence of Various Substances:

Extremely flammable in presence of open flames and sparks, of heat.

Non-flammable in presence of shocks.

Explosion Hazards in Presence of Various Substances:

Risks of explosion of the product in presence of static discharge: Not available.

Explosive in presence of heat, of acids, of alkalis.

Non-explosive in presence of shocks.

Fire Fighting Media and Instructions:

Flammable liquid, soluble or dispersed in water.

SMALL FIRE: Use DRY chemical powder.

LARGE FIRE: Use alcohol foam, water spray or fog. Cool containing vessels with water jet in order to prevent

pressure build-up, autoignition or explosion.

Special Remarks on Fire Hazards: When heated to decomposition it emits acrid smoke and fumes.

Special Remarks on Explosion Hazards:

Hazardous or explosive polymerization may occur with acids, alkaline materials, heat, strong bases, trace metals.

Forms explosive peroxides on exposure to air, heat or sunlight.


Section 6: Accidental Release Measures

Small Spill:

Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal


Large Spill:

Flammable liquid.

Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Absorb with DRY earth,

sand or other non-combustible material. Do not touch spilled material. Prevent entry into sewers, basements or

confined areas; dike if needed. Be careful that the product is not present at a concentration level above TLV.

Check TLV on the MSDS and with local authorities.


Section 7: Handling and Storage


Keep locked up.. Keep away from heat. Keep away from sources of ignition. Ground all equipment containing

material. Do not ingest. Do not breathe gas/fumes/ vapor/spray. Avoid contact with eyes. Wear suitable

protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek

medical advice immediately and show the container or the label. Keep away from incompatibles such as oxidizing

agents, combustible materials, organic materials, metals, acids, alkalis.


Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container tightly

closed and sealed until ready for use. Avoid all possible sources of ignition (spark or flame).


Section 8: Exposure Controls/Personal Protection

Engineering Controls:

Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their

respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the

work-station location.

Personal Protection:

Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent.

Gloves (impervious).

Personal Protection in Case of a Large Spill:

Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be

used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist

BEFORE handling this product.

Exposure Limits:

TWA: 25 (ppm) from ACGIH (TLV) [United States]

TWA: 200 STEL: 150 (ppm) from OSHA (PEL) [United States]

TWA: 360 STEL: 270 (mg/m3) from OSHA (PEL) [United States]

Consult local authorities for acceptable exposure limits.


Section 9: Physical and Chemical Properties

Physical state and appearance: Liquid. (Fuming liquid.)

p. 3

Odor: Fruity. Pungent. (Strong.)

Taste: Leafy green

Molecular Weight: 44.05 g/mole

Color: Colorless.

pH (1% soln/water): Not available.

Boiling Point: 21°C (69.8°F)

Melting Point: -123.5°C (-190.3°F)

Critical Temperature: 188°C (370.4°F)

Specific Gravity: 0.78 (Water = 1)

Vapor Pressure: 101.3 kPa (@ 20°C)

Vapor Density: 1.52 (Air = 1)

Volatility: Not available.

Odor Threshold: 0.21 ppm

Water/Oil Dist. Coeff.: Not available.

Ionicity (in Water): Not available.

Dispersion Properties: See solubility in water, diethyl ether, acetone.


Easily soluble in cold water, hot water.

Soluble in diethyl ether, acetone.

Miscible with benzene, gasoline, solvent naphtha, toluene, xylene, turpentine.

Solubility in water: 1000 g/l @ 25 deg. C.


Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.

Conditions of Instability: Heat, igition sources (flames, sparks), incompatible materials

Incompatibility with various substances:

Highly reactive with metals, acids, alkalis.

Reactive with oxidizing agents, combustible materials, organic materials.

Corrosivity: Non-corrosive in presence of glass.

Special Remarks on Reactivity:

Reacts with oxidizing materials, halogens, amines, strong alkalies (bases), and acids, cobalt acetate, phenols,

ketones, ammonia, hydrogen cyanide, hydrogen sulfide, hydrogen peroxide, mercury (II) salts (chlorate or

perchlorate), acid anhydrides, alcohols, iodine, isocyanates, phosphorus, phosphorus isocyanate,


It can slowly polymerize to paraldehyde.

Polymerization may occur in presence of acid traces causing exothermic reaction, increased vessel pressure, fire,

and explosion.


Impure material polymerizes readily in presence of traces of metals (iron) or acids.

Acetaldehyde is polymerized violently by concentrated sulfuric acid.

Acetaldehyde can dissolve rubber.

Special Remarks on Corrosivity: Not available.

Polymerization: Not available.


Section 11: Toxicological Information

Routes of Entry: Absorbed through skin. Eye contact. Inhalation. Ingestion.

Toxicity to Animals:


Acute oral toxicity (LD50): 661 mg/kg [Rat.].

Acute dermal toxicity (LD50): 3540 mg/kg [Rabbit].

Acute toxicity of the vapor (LC50): 23000 mg/m3 4 hours [Mouse].

Chronic Effects on Humans:

CARCINOGENIC EFFECTS: Classified 2B (Possible for human.) by IARC.

MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Mutagenic for bacteria and/or yeast.


May cause damage to the following organs: liver.

Other Toxic Effects on Humans:

Hazardous in case of ingestion, of inhalation (lung irritant).

Slightly hazardous in case of skin contact (irritant, permeator).

Special Remarks on Toxicity to Animals: Not available.

Special Remarks on Chronic Effects on Humans:

May cause adverse reproductive effects and birth defects(teratogenic) based on animal test data

May affect genetic material (mutagenic).

May cause cancer based on animal test data

Special Remarks on other Toxic Effects on Humans:

Acute Potential Health Effects:

Skin: Causes mild skin irritation. It can be absorbed through intact skin.

Eyes: Causes severe eye irritation. Eye splashes produce painful but superficial corneal injuries which heal rapidly.

Inhalation: It causes upper respiratory tract and mucous membrane irritation. It decreases the amount of pulmonary

macrophages. It may cause bronchitis. It may cause pulmonary edema, often the cause of delayed death. It may

affec respiration (dyspnea) and respiratory arrest and death may occur. It may affect behavior/central nervous and

cause central nervous system depression. Iirritation usually prevents voluntary exposure to airborne concentrations

high enough to cause CNS depression, although this effect has occurred in experimental animals. It may also affect

the peripheral nervous system and cardiovascular system (hypotension or hypertension, tachycardia, bradycardia),

kidneys (albuminuria)

Chronic Potential Health Effects:

Skin: Prolonged direct skin contact causes erythema and burns. Repeated exposure may cause dermatitis

secondary to primary irritation or sensitization.

Ingestion: Symptoms of chronic Acetaldehyde exposure may resemble those of chronic alcoholism. Acetaldehyde is

the a metabolite of ethanol in humans and has been implicated as the active agent damaging the liver in

ethanol-induced liver disease.


Section 12: Ecological Information

Ecotoxicity: Not available.

BOD5 and COD: Not available.

Products of Biodegradation:

Possibly hazardous short term degradation products are not likely. However, long term degradation products may


Toxicity of the Products of Biodegradation: The products of degradation are less toxic than the product itself.

Special Remarks on the Products of Biodegradation: Not available.


Section 13: Disposal Considerations

Waste Disposal:

Waste must be disposed of in accordance with federal, state and local environmental

control regulations.


Section 14: Transport Information

DOT Classification: CLASS 3: Flammable liquid.

Identification: : Acetaldehyde UNNA: 1089 PG: I

Special Provisions for Transport: Marine Pollutant


Section 15: Other Regulatory Information

Federal and State Regulations:

California prop. 65: This product contains the following ingredients for which the State of California has found to

cause cancer, birth defects or other reproductive harm, which would require a warning under the statute:


California prop. 65 (no significant risk level): Acetaldehyde: 0.09 mg/day (value)

California prop. 65: This product contains the following ingredients for which the State of California has found to

cause cancer which would require a warning under the statute: Acetaldehyde

Connecticut hazardous material survey.: Acetaldehyde

Illinois toxic substances disclosure to employee act: Acetaldehyde

Illinois chemical safety act: Acetaldehyde

New York release reporting list: Acetaldehyde

Rhode Island RTK hazardous substances: Acetaldehyde

Pennsylvania RTK: Acetaldehyde

Minnesota: Acetaldehyde

Massachusetts RTK: Acetaldehyde

Massachusetts spill list: Acetaldehyde

New Jersey: Acetaldehyde

New Jersey spill list: Acetaldehyde

New Jersey toxic catastrophe prevention act: Acetaldehyde

Louisiana spill reporting: Acetaldehyde

California Director's List of Hazardous Substances: Acetaldehyde

TSCA 8(b) inventory: Acetaldehyde

SARA 313 toxic chemical notification and release reporting: Acetaldehyde

CERCLA: Hazardous substances.: Acetaldehyde: 1000 lbs. (453.6 kg)

Other Regulations:

OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).

EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.

Other Classifications:

WHMIS (Canada):

CLASS B-2: Flammable liquid with a flash point lower than 37.8°C (100°F).

CLASS D-2A: Material causing other toxic effects (VERY TOXIC).


p. 6

R12- Extremely flammable.

R36/37/38- Irritating to eyes,

respiratory system and skin.

R40- Possible risks of irreversible


S16- Keep away from sources of ignition - No


S33- Take precautionary measures against

static discharges.

S36/37/39- Wear suitable protective clothing,

gloves and eye/face protection.

HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 4

Reactivity: 0

Personal Protection: j

National Fire Protection Association (U.S.A.):

Health: 3

Flammability: 4

Reactivity: 2

Specific hazard:

Protective Equipment:

Gloves (impervious).

Lab coat.

Vapor respirator. Be sure to use an

approved/certified respirator or

equivalent. Wear appropriate respirator

when ventilation is inadequate.

Splash goggles.


Section 16: Other Information


-Hawley, G.G.. The Condensed Chemical Dictionary, 11e ed., New York N.Y., Van Nostrand Reinold, 1987.

-Liste des produits purs tératogènes, mutagènes, cancérogènes. Répertoire toxicologique de la Commission de la Santé

et de la Sécurité du Travail du Québec.

-Material safety data sheet emitted by: la Commission de la Santé et de la Sécurité du Travail du Québec.

-SAX, N.I. Dangerous Properties of Indutrial Materials. Toronto, Van Nostrand Reinold, 6e ed. 1984.

-Guide de la loi et du règlement sur le transport des marchandises dangeureuses au canada. Centre de conformité

internatinal Ltée. 1986.

Other Special Considerations: Not available.

Created: 10/09/2005 03:35 PM

Last Updated: 11/06/2008 12:00 PM