2-Methyl Pyridine (Picoline) MSDS
Section 1: Chemical Product and Company Identification
Product Name: 2-Methyl Pyridine (Picoline)
Catalog Codes: SLP2989
CAS#: 109-06-8
RTECS: TJ4900000
TSCA: TSCA 8(b) inventory: 2-Methyl Pyridine (Picoline)
CI#: Not available.
Synonym: 2-Methylpyridine
Chemical Name: 2-Picoline
Chemical Formula: C6-H7-N
Section 2: Composition and Information on Ingredients
Composition:
Name CAS # % by Weight
{2-}Picoline 109-06-8 100
Toxicological Data on Ingredients: 2-Picoline: ORAL (LD50): Acute: 790 mg/kg [Rat]. 674 mg/kg [Mouse]. DERMAL (LD50):
Acute: 410 ul/kg [Rabbit].
Section 3: Hazards Identification
Potential Acute Health Effects:
Hazardous in case of skin contact (permeator), of eye contact (irritant), of ingestion, of inhalation. Slightly
hazardous in case of skin contact (irritant).
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Not available.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
Repeated or prolonged exposure is not known to aggravate medical condition.
Section 4: First Aid Measures
Eye Contact:
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at
least 15 minutes. Cold water may be used. Get medical attention.
Skin Contact:
In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove
contaminated clothing and shoes. Cold water may be used.Wash clothing before reuse. Thoroughly clean shoes
before reuse. Get medical attention.
Serious Skin Contact:
Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate
medical attention.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention.
Serious Inhalation:
Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or
waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth
resuscitation. Seek medical attention.
Ingestion:
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight
clothing such as a collar, tie, belt or waistband.
Serious Ingestion: Not available.
Section 5: Fire and Explosion Data
Flammability of the Product: Flammable.
Auto-Ignition Temperature: 538°C (1000.4°F)
Flash Points: OPEN CUP: 38.889°C (102°F).
Flammable Limits: Not available.
Products of Combustion: These products are carbon oxides (CO, CO2).
Fire Hazards in Presence of Various Substances:
Flammable in presence of open flames and sparks, of heat.
Non-flammable in presence of shocks.
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
Fire Fighting Media and Instructions:
Flammable liquid, soluble or dispersed in water.
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use alcohol foam, water spray or fog. Cool containing vessels with water jet in order to prevent
pressure build-up, autoignition or explosion.
Special Remarks on Fire Hazards: Not available.
Special Remarks on Explosion Hazards:
ADDITION OF 30% PEROXIDE & SULFURIC ACID TO 2-METHYLPYRIDINE & IRON(II)
SULFATE CAUSED SUDDEN EXOTHERM, FOLLOWED BY VAPOR PHASE EXPLOSION & IGNITION.
Section 6: Accidental Release Measures
Small Spill:
Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal
container.
Large Spill:
Flammable liquid.
Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Absorb with DRY earth,
sand or other non-combustible material. Do not touch spilled material. Prevent entry into sewers, basements or
confined areas; dike if needed. Be careful that the product is not present at a concentration level above TLV.
Check TLV on the MSDS and with local authorities.
Section 7: Handling and Storage
Precautions:
Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not
ingest. Do not breathe gas/fumes/ vapor/spray. Wear suitable protective clothing. In case of insufficient
ventilation, wear suitable respiratory equipment. If ingested, seek medical advice immediately and show the
container or the label. Avoid contact with skin and eyes. Keep away from incompatibles such as oxidizing agents.
Storage:
Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container tightly
closed and sealed until ready for use. Avoid all possible sources of ignition (spark or flame).
Section 8: Exposure Controls/Personal Protection
Engineering Controls:
Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their
respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the
work-station location.
Personal Protection:
Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent.
Gloves.
Personal Protection in Case of a Large Spill:
Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be
used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist
BEFORE handling this product.
Exposure Limits:
TWA: 7.6 STEL: 19 (mg/m3) from AIHA [United States]
TWA: 2 STEL: 5 (ppm) from AIHA [United States]
Consult local authorities for acceptable exposure limits.
Section 9: Physical and Chemical Properties
Physical state and appearance: Liquid.
Odor: Unpleasant (Strong.)
Taste: Not available.
Molecular Weight: 93.13 g/mole
Color: Colorless.
pH (1% soln/water): Not available.
Boiling Point: 128.5°C (263.3°F)
Melting Point: -70°C (-94°F)
Critical Temperature: Not available.
Specific Gravity: 0.943 (Water = 1)
Vapor Pressure: 1.5 kPa (@ 25°C)
Vapor Density: 3.2 (Air = 1)
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff.: The product is more soluble in oil; log(oil/water) = 1.1
Ionicity (in Water): Not available.
Dispersion Properties: See solubility in water, diethyl ether, acetone.
Solubility:
Easily soluble in cold water, hot water.
Soluble in diethyl ether, acetone.
Miscible with alcohol
Section 10: Stability and Reactivity Data
Stability: The product is stable.
Instability Temperature: Not available.
Conditions of Instability: Excess heat, ignition sources (flames, sparks), incompatible materials
Incompatibility with various substances: Reactive with oxidizing agents.
Corrosivity: Not available.
Special Remarks on Reactivity: Incompatible with Hydrogen Peroxide, iron (II) sulfate, sulfuric acid.
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
Section 11: Toxicological Information
Routes of Entry: Absorbed through skin. Dermal contact. Eye contact. Inhalation.
Toxicity to Animals:
Acute oral toxicity (LD50): 674 mg/kg [Mouse].
Acute dermal toxicity (LD50): 410 mg/kg [Rabbit].
Chronic Effects on Humans: Not available.
Other Toxic Effects on Humans:
Hazardous in case of skin contact (permeator), of ingestion, of inhalation.
Slightly hazardous in case of skin contact (irritant).
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: May affect genetic material (mutagenic)
Special Remarks on other Toxic Effects on Humans:
Acute Potential Health Effects:
Skin: Causes skin irritation. May be absorbed through skin. It may be harmful if absorbed through skin.
Eyes: Causes eye irritation.
Inhalation: Causes irritation of the respiratory tract and mucous membranes. Inhalation of vapors may affect
behavior/central nervous system (dizziness, giddiness), cardiovascular system( flushing of face, increase in heart
rate), respiration (increase in respiration rate), and may cause suffocation, nausea, and vomiting.
Ingestion: May cause digestive tract irritation with diarrhea. May affect behavior/central nervous system (ataxia,
weakness, somnolence, convulsions, excitement), and metabolism (weigjt loss).
Chronic Potential Health Effects:
Ingestion: Prolonged or repeated ingestion may affect blood (change in clotting factors, changes in cell count,
thromobocytopenia)
Section 12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Products of Biodegradation:
Possibly hazardous short term degradation products are not likely. However, long term degradation products may
arise.
Toxicity of the Products of Biodegradation: The products of degradation are less toxic than the product itself.
Special Remarks on the Products of Biodegradation: Not available.
Section 13: Disposal Considerations
Waste Disposal:
Waste must be disposed of in accordance with federal, state and local environmental
control regulations.
Section 14: Transport Information
DOT Classification: CLASS 3: Flammable liquid.
Identification: : Picolines UNNA: 2313 PG: III
Special Provisions for Transport: Not available.
Section 15: Other Regulatory Information
Federal and State Regulations:
Connecticut hazardous material survey.: 2-Picoline
Illinois chemical safety act: 2-Picoline
New York release reporting list: 2-Picoline
Pennsylvania RTK: 2-Picoline
Massachusetts RTK: 2-Picoline
Massachusetts spill list: 2-Picoline
New Jersey: 2-Picoline
New Jersey spill list: 2-Picoline
Louisiana spill reporting: 2-Picoline
TSCA 8(b) inventory: 2-Picoline
TSCA 4(a) proposed test rules: 2-Picoline
p. 5
TSCA 8(a) IUR: 2-Picoline
TSCA 8(d) H and S data reporting: 2-Picoline: effective: 9/10/84; sunset: 9/10/94
SARA 313 toxic chemical notification and release reporting: 2-Picoline
CERCLA: Hazardous substances.: 2-Picoline: 5000 lbs. (2268 kg)
Other Regulations:
OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.
Other Classifications:
WHMIS (Canada):
CLASS B-2: Flammable liquid with a flash point lower than 37.8°C (100°F).
CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).
DSCL (EEC):
R10- Flammable.
R21/22- Harmful in contact with skin
and if swallowed.
R36- Irritating to eyes.
S2- Keep out of the reach of children.
S36/37- Wear suitable protective clothing and
gloves.
S46- If swallowed, seek medical advice
immediately and show this container or label.
HMIS (U.S.A.):
Health Hazard: 2
Fire Hazard: 2
Reactivity: 0
Personal Protection: h
National Fire Protection Association (U.S.A.):
Health: 2
Flammability: 2
Reactivity: 0
Specific hazard:
Protective Equipment:
Gloves.
Lab coat.
Vapor respirator. Be sure to use an
approved/certified respirator or
equivalent. Wear appropriate respirator
when ventilation is inadequate.
Splash goggles.
Section 16: Other Information
References: Not available.
Other Special Considerations: Not available.
Created: 10/10/2005 11:27 AM
Last Updated: 11/06/2008 12:00 PM