2-Thiouracil for Synthesis MSDS
Section 1: Chemical Product and Company Identification
Product Name: 2-Thiouracil for Synthesis
Catalog Codes: SLM1270
CAS#: 141-90-2
RTECS: YR0875000
TSCA: TSCA 8(b) inventory: 2-Thiouracil for Synthesis
CI#: Not available.
Synonym:
2,3-Dihydro-6-methyl-2-thioxo-4(1H)-pyrimidinone
Chemical Name: Not available.
Chemical Formula: C5H6N2OS
Section 2: Composition and Information on Ingredients
Composition:
Name CAS # % by Weight
{2-} Thiouracil for Synthesis 141-90-2 100
Toxicological Data on Ingredients: 6-Methyl-2-thiouracil: ORAL (LD50): Acute: 1500 mg/kg [Rat].
Section 3: Hazards Identification
Potential Acute Health Effects: Hazardous in case of skin contact (irritant, permeator), of eye contact (irritant), of ingestion,
of inhalation.
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: Classified + (PROVEN) by OSHA. Classified 2B (Possible for human.) by IARC.
MUTAGENIC EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available.
DEVELOPMENTAL TOXICITY: Not available.
Repeated or prolonged exposure is not known to aggravate medical condition.
Section 4: First Aid Measures
Eye Contact: Check for and remove any contact lenses. Do not use an eye ointment. Seek medical attention.
Skin Contact:
After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin
with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin.
Cover the irritated skin with an emollient. If irritation persists, seek medical attention.
Serious Skin Contact:
Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate
medical attention.
Inhalation: Allow the victim to rest in a well ventilated area. Seek immediate medical attention.
Serious Inhalation: Not available.
Ingestion:
Do not induce vomiting. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible
indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Loosen
tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth
resuscitation. Seek immediate medical attention.
Serious Ingestion: Not available.
Section 5: Fire and Explosion Data
Flammability of the Product: Non-flammable.
Auto-Ignition Temperature: Not applicable.
Flash Points: Not applicable.
Flammable Limits: Not applicable.
Products of Combustion: These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...).
Fire Hazards in Presence of Various Substances: Not available.
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
Fire Fighting Media and Instructions:
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks on Fire Hazards: Not available.
Special Remarks on Explosion Hazards: Not available.
Section 6: Accidental Release Measures
Small Spill:
Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by
spreading water on the contaminated surface and dispose of according to local and regional authority
requirements.
Large Spill:
Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary
system.
Section 7: Handling and Storage
Precautions:
Keep locked up Do not ingest. Do not breathe gas/fumes/ vapour/spray. Wear suitable protective clothing In
case of insufficient ventilation, wear suitable respiratory equipment If ingested, seek medical advice immediately
and show the container or the label. Keep container tightly closed and in a well-ventilated place. Avoid contact
with skin and eyes
Storage:
Carcinogenic, teratogenic or mutagenic materials should be stored in a separate locked safety storage cabinet or
room.
Section 8: Exposure Controls/Personal Protection
Engineering Controls: No special ventilation requirements.
Personal Protection:
Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent.
Gloves.
Personal Protection in Case of a Large Spill:
Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be
used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist
BEFORE handling this product.
Exposure Limits: Not available.
Section 9: Physical and Chemical Properties
Physical state and appearance: Not available.
Odor: Not available.
Taste: Not available.
Molecular Weight: Not available.
Color: Not available.
pH (1% soln/water): Not available.
Boiling Point: Not available.
Melting Point: 150°C (302°F)
Critical Temperature: Not available.
Specific Gravity: Not available.
Vapor Pressure: Not available.
Vapor Density: Not available.
Volatility: Not available.
Odor Threshold: Not available.
Water/Oil Dist. Coeff.: Not available.
Ionicity (in Water): Not available.
Dispersion Properties: Not available.
Solubility: Not available.
Section 10: Stability and Reactivity Data
Stability: The product is stable.
Instability Temperature: Not available.
Conditions of Instability: Not available.
Incompatibility with various substances: Not available.
Corrosivity: Non-corrosive in presence of glass.
Special Remarks on Reactivity: Not available.
Special Remarks on Corrosivity: Not available.
Polymerization: No.
Section 11: Toxicological Information
Routes of Entry: Dermal contact. Eye contact. Inhalation. Ingestion.
Toxicity to Animals: Acute oral toxicity (LD50): 1500 mg/kg [Rat].
Chronic Effects on Humans: CARCINOGENIC EFFECTS: Classified + (PROVEN) by OSHA. Classified 2B (Possible for
human.) by IARC.
Other Toxic Effects on Humans: Hazardous in case of skin contact (irritant, permeator), of ingestion, of inhalation.
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans: Not available.
Special Remarks on other Toxic Effects on Humans: Not available.
Section 12: Ecological Information
Ecotoxicity: Not available.
BOD5 and COD: Not available.
Products of Biodegradation:
Possibly hazardous short term degradation products are not likely. However, long term degradation products may
arise.
Toxicity of the Products of Biodegradation: The products of degradation are more toxic.
Special Remarks on the Products of Biodegradation: Not available.
Section 13: Disposal Considerations
Waste Disposal:
Section 14: Transport Information
DOT Classification: Not a DOT controlled material (United States).
Identification: Not applicable.
Special Provisions for Transport: Not applicable.
Section 15: Other Regulatory Information
Federal and State Regulations:
California prop. 65: This product contains the following ingredients for which the State of California has found to
cause cancer, birth defects or other reproductive harm, which would require a warning under the statute:
6-Methyl-2-thiouracil
California prop. 65: This product contains the following ingredients for which the State of California has found to
cause cancer which would require a warning under the statute: 6-Methyl-2-thiouracil
Pennsylvania RTK: 6-Methyl-2-thiouracil
Florida: 6-Methyl-2-thiouracil
Minnesota: 6-Methyl-2-thiouracil
Massachusetts RTK: 6-Methyl-2-thiouracil
New Jersey: 6-Methyl-2-thiouracil
TSCA 8(b) inventory: 6-Methyl-2-thiouracil
CERCLA: Hazardous substances.: 6-Methyl-2-thiouracil
Other Regulations: OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).
Other Classifications:
WHMIS (Canada): CLASS D-2A: Material causing other toxic effects (VERY TOXIC).
DSCL (EEC):
R22- Harmful if swallowed.
R36/38- Irritating to eyes and skin.
R45- May cause cancer.
HMIS (U.S.A.):
Health Hazard: 2
Fire Hazard: 0
Reactivity: 0
Personal Protection: h
National Fire Protection Association (U.S.A.):
Health: 2
Flammability: 0
Reactivity: 0
Specific hazard:
Protective Equipment:
Gloves.
Lab coat.
Vapor respirator. Be sure to use an
approved/certified respirator or
equivalent. Wear appropriate respirator
when ventilation is inadequate.
Splash goggles.
Section 16: Other Information
References: Not available.
Other Special Considerations: Not available.
Created: 10/10/2005 10:49 AM
Last Updated: 11/06/2008 12:00 PM