2-Thiouracil for Synthesis MSDS

2-Thiouracil for Synthesis MSDS

 

Section 1: Chemical Product and Company Identification

Product Name: 2-Thiouracil for Synthesis

Catalog Codes: SLM1270

CAS#: 141-90-2

RTECS: YR0875000

TSCA: TSCA 8(b) inventory: 2-Thiouracil for Synthesis

CI#: Not available.

Synonym:

2,3-Dihydro-6-methyl-2-thioxo-4(1H)-pyrimidinone

Chemical Name: Not available.

Chemical Formula: C5H6N2OS

 

Section 2: Composition and Information on Ingredients

Composition:

Name CAS # % by Weight

{2-} Thiouracil for Synthesis 141-90-2 100

Toxicological Data on Ingredients: 6-Methyl-2-thiouracil: ORAL (LD50): Acute: 1500 mg/kg [Rat].

 

Section 3: Hazards Identification

Potential Acute Health Effects: Hazardous in case of skin contact (irritant, permeator), of eye contact (irritant), of ingestion,

of inhalation.

Potential Chronic Health Effects:

CARCINOGENIC EFFECTS: Classified + (PROVEN) by OSHA. Classified 2B (Possible for human.) by IARC.

MUTAGENIC EFFECTS: Not available.

TERATOGENIC EFFECTS: Not available.

DEVELOPMENTAL TOXICITY: Not available.

Repeated or prolonged exposure is not known to aggravate medical condition.

 

Section 4: First Aid Measures

Eye Contact: Check for and remove any contact lenses. Do not use an eye ointment. Seek medical attention.

Skin Contact:

After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin

with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin.

Cover the irritated skin with an emollient. If irritation persists, seek medical attention.

Serious Skin Contact:

Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate

medical attention.

Inhalation: Allow the victim to rest in a well ventilated area. Seek immediate medical attention.

Serious Inhalation: Not available.

Ingestion:

Do not induce vomiting. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible

indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Loosen

tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth

resuscitation. Seek immediate medical attention.

Serious Ingestion: Not available.

 

Section 5: Fire and Explosion Data

Flammability of the Product: Non-flammable.

Auto-Ignition Temperature: Not applicable.

Flash Points: Not applicable.

Flammable Limits: Not applicable.

Products of Combustion: These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...).

Fire Hazards in Presence of Various Substances: Not available.

Explosion Hazards in Presence of Various Substances:

Risks of explosion of the product in presence of mechanical impact: Not available.

Risks of explosion of the product in presence of static discharge: Not available.

Fire Fighting Media and Instructions:

SMALL FIRE: Use DRY chemical powder.

LARGE FIRE: Use water spray, fog or foam. Do not use water jet.

Special Remarks on Fire Hazards: Not available.

Special Remarks on Explosion Hazards: Not available.

 

Section 6: Accidental Release Measures

Small Spill:

Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by

spreading water on the contaminated surface and dispose of according to local and regional authority

requirements.

Large Spill:

Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary

system.

 

Section 7: Handling and Storage

Precautions:

Keep locked up Do not ingest. Do not breathe gas/fumes/ vapour/spray. Wear suitable protective clothing In

case of insufficient ventilation, wear suitable respiratory equipment If ingested, seek medical advice immediately

and show the container or the label. Keep container tightly closed and in a well-ventilated place. Avoid contact

with skin and eyes

Storage:

Carcinogenic, teratogenic or mutagenic materials should be stored in a separate locked safety storage cabinet or

room.

 

Section 8: Exposure Controls/Personal Protection

Engineering Controls: No special ventilation requirements.

Personal Protection:

Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent.

Gloves.

Personal Protection in Case of a Large Spill:

Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be

used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist

BEFORE handling this product.

Exposure Limits: Not available.

 

Section 9: Physical and Chemical Properties

Physical state and appearance: Not available.

Odor: Not available.

Taste: Not available.

Molecular Weight: Not available.

Color: Not available.

pH (1% soln/water): Not available.

Boiling Point: Not available.

Melting Point: 150°C (302°F)

Critical Temperature: Not available.

Specific Gravity: Not available.

Vapor Pressure: Not available.

Vapor Density: Not available.

Volatility: Not available.

Odor Threshold: Not available.

Water/Oil Dist. Coeff.: Not available.

Ionicity (in Water): Not available.

Dispersion Properties: Not available.

Solubility: Not available.

 

Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.

Conditions of Instability: Not available.

Incompatibility with various substances: Not available.

Corrosivity: Non-corrosive in presence of glass.

Special Remarks on Reactivity: Not available.

Special Remarks on Corrosivity: Not available.

Polymerization: No.

 

Section 11: Toxicological Information

Routes of Entry: Dermal contact. Eye contact. Inhalation. Ingestion.

Toxicity to Animals: Acute oral toxicity (LD50): 1500 mg/kg [Rat].

Chronic Effects on Humans: CARCINOGENIC EFFECTS: Classified + (PROVEN) by OSHA. Classified 2B (Possible for

human.) by IARC.

Other Toxic Effects on Humans: Hazardous in case of skin contact (irritant, permeator), of ingestion, of inhalation.

Special Remarks on Toxicity to Animals: Not available.

Special Remarks on Chronic Effects on Humans: Not available.

Special Remarks on other Toxic Effects on Humans: Not available.

 

Section 12: Ecological Information

Ecotoxicity: Not available.

BOD5 and COD: Not available.

Products of Biodegradation:

Possibly hazardous short term degradation products are not likely. However, long term degradation products may

arise.

Toxicity of the Products of Biodegradation: The products of degradation are more toxic.

Special Remarks on the Products of Biodegradation: Not available.

 

Section 13: Disposal Considerations

Waste Disposal:

 

Section 14: Transport Information

DOT Classification: Not a DOT controlled material (United States).

Identification: Not applicable.

Special Provisions for Transport: Not applicable.

 

Section 15: Other Regulatory Information

Federal and State Regulations:

California prop. 65: This product contains the following ingredients for which the State of California has found to

cause cancer, birth defects or other reproductive harm, which would require a warning under the statute:

6-Methyl-2-thiouracil

California prop. 65: This product contains the following ingredients for which the State of California has found to

cause cancer which would require a warning under the statute: 6-Methyl-2-thiouracil

Pennsylvania RTK: 6-Methyl-2-thiouracil

Florida: 6-Methyl-2-thiouracil

Minnesota: 6-Methyl-2-thiouracil

Massachusetts RTK: 6-Methyl-2-thiouracil

New Jersey: 6-Methyl-2-thiouracil

TSCA 8(b) inventory: 6-Methyl-2-thiouracil

CERCLA: Hazardous substances.: 6-Methyl-2-thiouracil

Other Regulations: OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).

Other Classifications:

WHMIS (Canada): CLASS D-2A: Material causing other toxic effects (VERY TOXIC).

DSCL (EEC):

R22- Harmful if swallowed.

R36/38- Irritating to eyes and skin.

R45- May cause cancer.

HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 0

Reactivity: 0

Personal Protection: h

National Fire Protection Association (U.S.A.):

Health: 2

Flammability: 0

Reactivity: 0

Specific hazard:

Protective Equipment:

Gloves.

Lab coat.

Vapor respirator. Be sure to use an

approved/certified respirator or

equivalent. Wear appropriate respirator

when ventilation is inadequate.

Splash goggles.

 

Section 16: Other Information

References: Not available.

Other Special Considerations: Not available.

Created: 10/10/2005 10:49 AM

Last Updated: 11/06/2008 12:00 PM