4-Chlorophenol for Synthesis MSDS

Section 1: Chemical Product and Company Identification

Product Name: 4-Chlorophenol for Synthesis

Catalog Codes: SLC1279

CAS#: 106-48-9

RTECS: SK2800000

TSCA: TSCA 8(b) inventory: 4-Chlorophenol for Synthesis

CI#: Not available.

Synonym: p-Chlorophenol

Chemical Name: 4-Chlorophenol for Synthesis

Chemical Formula: C6-H5-Cl-O

Section 2: Composition and Information on Ingredients

Composition:

Name CAS # % by Weight

{4-}Chlorophenol for Synthesis 106-48-9 100

Toxicological Data on Ingredients: 4-Chlorophenol for Synthesis : ORAL (LD50): Acute: 367 mg/kg [Mouse]. 670 mg/kg [Rat]. DERMAL

(LD50): Acute: 1500 mg/kg [Rat].

Section 3: Hazards Identification

Potential Acute Health Effects:

Very hazardous in case of skin contact (irritant), of eye contact (irritant). Corrosive to eyes and skin. The amount

of tissue damage depends on length of contact. Eye contact can result in corneal damage or blindness. Skin

contact can produce inflammation and blistering. Inhalation of dust will produce irritation to gastro-intestinal or

respiratory tract, characterized by burning, sneezing and coughing. Severe over-exposure can produce lung

damage, choking, unconsciousness or death. Inflammation of the eye is characterized by redness, watering, and

itching. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering.

Potential Chronic Health Effects:

CARCINOGENIC EFFECTS: Classified 2B (Possible for human.) by IARC.

MUTAGENIC EFFECTS: Not available.

TERATOGENIC EFFECTS: Not available.

DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/male, Development toxin [POSSIBLE].

The substance may be toxic to liver, brain, gastrointestinal tract, upper respiratory tract, central nervous system

 (CNS).

Repeated or prolonged exposure to the substance can produce target organs damage. Repeated exposure of the

eyes to a low level of dust can produce eye irritation. Repeated skin exposure can produce local skin destruction,

or dermatitis. Repeated inhalation of dust can produce varying degree of respiratory irritation or lung damage.

Section 4: First Aid Measures

Eye Contact:

Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at

least 15 minutes. Cold water may be used. WARM water MUST be used. Get medical attention immediately.

Skin Contact:

In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated

clothing and shoes. Cover the irritated skin with an emollient. Wash clothing before reuse. Thoroughly clean

shoes before reuse. Get medical attention immediately.

Serious Skin Contact:

Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate

medical attention.

Inhalation:

If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get

medical attention.

Serious Inhalation:

Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or

waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth

resuscitation. WARNING: It may be hazardous to the person providing aid to give mouth-to-mouth resuscitation

when the inhaled material is toxic, infectious or corrosive. Seek immediate medical attention.

Ingestion:

Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an

unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight

clothing such as a collar, tie, belt or waistband.

Serious Ingestion: Not available.

Section 5: Fire and Explosion Data

Flammability of the Product: May be combustible at high temperature.

Auto-Ignition Temperature: Not available.

Flash Points: CLOSED CUP: 115°C (239°F).

Flammable Limits: Not available.

Products of Combustion: These products are carbon oxides (CO, CO2), halogenated compounds.

Fire Hazards in Presence of Various Substances: Flammable in presence of open flames and sparks.

Explosion Hazards in Presence of Various Substances:

Risks of explosion of the product in presence of mechanical impact: Not available.

Risks of explosion of the product in presence of static discharge: Not available.

Fire Fighting Media and Instructions:

SMALL FIRE: Use DRY chemical powder.

LARGE FIRE: Use water spray, fog or foam. Do not use water jet.

Special Remarks on Fire Hazards: Not available.

Special Remarks on Explosion Hazards: Not available.

Section 6: Accidental Release Measures

Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container.

Large Spill:

Corrosive solid.

Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray to

reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all ignition

sources. Call for assistance on disposal. Be careful that the product is not present at a concentration level above

TLV. Check TLV on the MSDS and with local authorities.

Section 7: Handling and Storage

Precautions:

Keep locked up.. Keep container dry. Keep away from heat. Keep away from sources of ignition. Empty

containers pose a fire risk, evaporate the residue under a fume hood. Ground all equipment containing material.

Do not ingest. Do not breathe dust. Never add water to this product. If ingested, seek medical advice

immediately and show the container or the label. Avoid contact with skin and eyes.

Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area.

Section 8: Exposure Controls/Personal Protection

Engineering Controls:

Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below

recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to

airborne contaminants below the exposure limit.

Personal Protection:

Splash goggles. Synthetic apron. Dust respirator. Be sure to use an approved/certified respirator or equivalent.

Gloves.

Personal Protection in Case of a Large Spill:

Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used

to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist

BEFORE handling this product.

Exposure Limits:

TWA: 0.5 (mg/m3) [Denmark] [1993] SKIN

STEL: 1 (mg/m3) [Russia] [1993] SKIN

TWA: 0.5 (mg/m3) [Sweden] [1999] SKINConsult local authorities for acceptable exposure limits.

Section 9: Physical and Chemical Properties

Physical state and appearance: Solid.

Odor: Phenolic-like.

Taste: Not available.

Molecular Weight: 128.56 g/mole

Color: White to off-white

pH (1% soln/water): Not available.

Boiling Point: 220°C (428°F)

Melting Point: 44°C (111.2°F)

Critical Temperature: Not available.

Specific Gravity: Not available.

Vapor Pressure: Not applicable.

Vapor Density: 4.43 (Air = 1)

Volatility: Not available.

Odor Threshold: 30 ppm

Water/Oil Dist. Coeff.: Not available.

Ionicity (in Water): Not available.

Dispersion Properties:

Dispersed in methanol, diethyl ether, n-octanol.

Very slightly dispersed in cold water, hot water.

See solubility in methanol, diethyl ether, n-octanol, acetone.

Solubility:

Soluble in methanol, diethyl ether, n-octanol, acetone.

Very slightly soluble in cold water, hot water.

Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.

Conditions of Instability: Not available.

Incompatibility with various substances: Not available.

Corrosivity: Not available.

Special Remarks on Reactivity: Not available.

Special Remarks on Corrosivity: Not available.

Polymerization: Will not occur.

Section 11: Toxicological Information

Routes of Entry: Absorbed through skin. Eye contact.

Toxicity to Animals:

Acute oral toxicity (LD50): 367 mg/kg [Mouse].

Acute dermal toxicity (LD50): 1500 mg/kg [Rat].

Chronic Effects on Humans:

CARCINOGENIC EFFECTS: Classified 2B (Possible for human.) by IARC.

DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/male, Development toxin [POSSIBLE].

May cause damage to the following organs: liver, brain, gastrointestinal tract, upper respiratory tract, central

nervous system (CNS).

Other Toxic Effects on Humans: Very hazardous in case of skin contact (irritant).

Special Remarks on Toxicity to Animals: Not available.

Special Remarks on Chronic Effects on Humans: Not available.

Special Remarks on other Toxic Effects on Humans: Not available.

Section 12: Ecological Information

Ecotoxicity: Not available.

BOD5 and COD: Not available.

Products of Biodegradation:

Possibly hazardous short term degradation products are not likely. However, long term degradation products may

arise.

Toxicity of the Products of Biodegradation: The products of degradation are as toxic as the product itself.

Special Remarks on the Products of Biodegradation: Not available.

Section 13: Disposal Considerations

Waste Disposal:

Section 14: Transport Information

DOT Classification: CLASS 6.1: Poisonous material.

Identification: : Chlorophenols, Solid UN2020 PG: III

Special Provisions for Transport: Not available.

Section 15: Other Regulatory Information

Federal and State Regulations:

Pennsylvania RTK: 4-Chlorophenol

Minnesota: 4-Chlorophenol

Michigan critical material: 4-Chlorophenol

Massachusetts RTK: 4-Chlorophenol

New Jersey: 4-Chlorophenol

New Jersey spill list: 4-Chlorophenol

TSCA 8(b) inventory: 4-Chlorophenol

TSCA 8(d) H and S data reporting: 4-Chlorophenol: June 1999

Other Regulations:

OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).

EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.

Other Classifications:

WHMIS (Canada):

CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).

CLASS D-2A: Material causing other toxic effects (VERY TOXIC).

DSCL (EEC):

R20/21/22- Harmful by inhalation, in

contact with skin and if swallowed.

HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 1

Reactivity: 0

Personal Protection:

National Fire Protection Association (U.S.A.):

Health: 3

Flammability: 1

Reactivity: 0

Specific hazard:

Protective Equipment:

Gloves.

Synthetic apron.

Dust respirator. Be sure to use an

approved/certified respirator or

equivalent. Wear appropriate respirator

when ventilation is inadequate.

Splash goggles.

Section 16: Other Information

References: Not available.

Other Special Considerations: Not available.

Created: 10/09/2005 04:53 PM

Last Updated: 11/06/2008 12:00 PM