n-Butyric Acid for synthesis MSDS

Section 1: Chemical Product and Company Identification

Product Name: n-Butyric Acid for synthesis

Catalog Codes: SLB3790

CAS#: 106-31-0

RTECS: Et7090000

TSCA: TSCA 8(b) inventory: n-Butyric Acid for synthesis

CI#: Not available.

Synonym: Butanoic acid, anhydride; Butanoic anhydride;

Butyric acid anhydride; Butyryl oxide; n-Butyric acid

anhydride

Chemical Name: n-Butyric Acid for synthesis

Chemical Formula: C8-H14-O3

Section 2: Composition and Information on Ingredients

Composition:

Name CAS # % by Weight

n-Butyric Acid for synthesis 106-31-0 100

Toxicological Data on Ingredients: n-Butyric Acid for synthesis: ORAL (LD50): Acute: 8790 mg/kg [Rat].

Section 3: Hazards Identification

Potential Acute Health Effects:

Very hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Hazardous in case of

skin contact (corrosive), of eye contact (corrosive). Slightly hazardous in case of skin contact (permeator). Liquid or spray

mist may produce tissue damage particularly on mucous membranes of eyes, mouth and respiratory tract. Skin contact may

produce burns. Inhalation of the spray mist may produce severe irritation of respiratory tract, characterized by coughing,

choking, or shortness of breath. Inflammation of the eye is characterized by redness, watering, and itching. Skin inflammation

is characterized by itching, scaling, reddening, or, occasionally, blistering.

Potential Chronic Health Effects:

Hazardous in case of skin contact (irritant), of eye contact (irritant). CARCINOGENIC EFFECTS: Not available. MUTAGENIC

EFFECTS: Not available. TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Not available. Repeated

or prolonged contact with spray mist may produce chronic eye irritation and severe skin irritation. Repeated or prolonged

exposure to spray mist may produce respiratory tract irritation leading to frequent attacks of bronchial infection.

Section 4: First Aid Measures

Eye Contact:

Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15

minutes. Cold water may be used. Get medical attention immediately.

Skin Contact:

In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing

and shoes. Cover the irritated skin with an emollient. Cold water may be used.Wash clothing before reuse. Thoroughly clean

shoes before reuse. Get medical attention immediately.

Serious Skin Contact:

Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical attention.

Inhalation:

If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical

attention immediately.

Serious Inhalation:

Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. If

breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation. WARNING: It may

be hazardous to the person providing aid to give mouth-to-mouth resuscitation when the inhaled material is toxic, infectious or

corrosive. Seek immediate medical attention.

Ingestion:

Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious

person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear.

Serious Ingestion: Not available.

Section 5: Fire and Explosion Data

Flammability of the Product: Flammable.

Auto-Ignition Temperature: 279°C (534.2°F)

Flash Points: CLOSED CUP: 54°C (129.2°F). OPEN CUP: 87°C (188.6°F).

Flammable Limits: LOWER: 0.9% UPPER: 5.8%

Products of Combustion: These products are carbon oxides (CO, CO2).

Fire Hazards in Presence of Various Substances:

Flammable in presence of open flames and sparks, of heat. Non-flammable in presence of shocks.

Explosion Hazards in Presence of Various Substances:

Risks of explosion of the product in presence of mechanical impact: Not available. Risks of explosion of the product in

presence of static discharge: Not available. Explosive in presence of heat. Slightly explosive in presence of moisture.

Fire Fighting Media and Instructions:

Flammable liquid, soluble or dispersed in water. SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use alcohol foam,

water spray or fog. Cool containing vessels with water jet in order to prevent pressure build-up, autoignition or explosion.

Special Remarks on Fire Hazards: COMBUSTIBLE. May burn, but does not ignite readily

Special Remarks on Explosion Hazards: Containers may explode if heated or contaminated with water.

Section 6: Accidental Release Measures

Small Spill:

Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste disposal container.

Large Spill:

Flammable liquid. Corrosive liquid. Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Absorb

with DRY earth, sand or other non-combustible material. Do not get water inside container. Do not touch spilled material.

Use water spray curtain to divert vapor drift. Prevent entry into sewers, basements or confined areas; dike if needed. Call for

assistance on disposal.

Section 7: Handling and Storage

Precautions:

Keep container dry. Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material.

Do not ingest. Do not breathe gas/fumes/ vapor/spray. Never add water to this product. In case of insufficient ventilation,

wear suitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoid

contact with skin and eyes. Keep away from incompatibles such as oxidizing agents, reducing agents, acids, alkalis.

Storage:

Store in a segregated and approved area. Keep container in a cool, well-ventilated area. Keep container tightly closed and

sealed until ready for use. Avoid all possible sources of ignition (spark or flame).

Section 8: Exposure Controls/Personal Protection

Engineering Controls:

Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respective

threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station location.

Personal Protection:

Face shield. Full suit. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Boots.

Personal Protection in Case of a Large Spill:

Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid

inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this

product.

Exposure Limits: Not available.

Section 9: Physical and Chemical Properties

Physical state and appearance: Liquid.

Odor: Pungent. Stench.

Taste: Not available.

Molecular Weight: 158.2 g/mole

Color: Colorless to light yellow. Clear

pH (1% soln/water): Not available.

Boiling Point: 199.4°C (390.9°F) - 201.4 C

Melting Point: -75°C (-103°F)

Critical Temperature: Not available.

Specific Gravity: 0.9668 (Water = 1)

Vapor Pressure: 0 kPa (@ 20°C)

Vapor Density: 5.4 (Air = 1)

Volatility: Not available.

Odor Threshold: Not available.

Water/Oil Dist. Coeff.: Not available.

Ionicity (in Water): Not available.

Dispersion Properties: See solubility in water, diethyl ether.

Solubility:

Soluble in cold water, diethyl ether. Soluble in alcohol and water with decomposition.

Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.

Conditions of Instability: Heat, ignition sources, water/moisture, incompatible materials

Incompatibility with various substances:

Reactive with oxidizing agents, reducing agents, acids, alkalis. Slightly reactive to reactive with moisture.

Corrosivity: Not available.

Special Remarks on Reactivity:

Moisture sensitive. It will react with water releasing toxic or corrosive gases and runoff. Also incompatible with alcohols.

Special Remarks on Corrosivity: Not available.

Polymerization: Will not occur.

Section 11: Toxicological Information

Routes of Entry: Absorbed through skin. Eye contact. Inhalation. Ingestion.

Toxicity to Animals: Acute oral toxicity (LD50): 8790 mg/kg [Rat].

Chronic Effects on Humans: Not available.

Other Toxic Effects on Humans:

Very hazardous in case of skin contact (irritant), of ingestion, . Hazardous in case of skin contact (corrosive), of eye contact

(corrosive), of inhalation (lung corrosive). Slightly hazardous in case of skin contact (permeator).

Special Remarks on Toxicity to Animals:

Lowest Published Lethal Dose: LDL [Mouse] - Route: Oral; Dose: 1000 mg/kg

Special Remarks on Chronic Effects on Humans: Not available.

Special Remarks on other Toxic Effects on Humans:

Acute Potential Health Effects: Skin: Causes severe irritation and burns. Eyes: Causes severe irritation and burns. Inhalation:

Causes respiratory tract irritation and chemical burns to the respiratory tract. Inhalation may also be fatal as a result of

spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis, and pulmonary edema. Ingestion: Causes

gastrointestinal tract irritation and burns. It may affect behavior (somnolence), liver, and urinary tract. Chronic Potential

Health Effects: Skin: Repeated or prolonged skin contact causes skin irritation. Eyes: Butyric anhydride causes persistent

eye irritation if contact with vapor is repeated and prolonged. It may produce chronic conjunctivitis. Inhalation: Repeated or

prolonged inhalation may affect respiration/respiratory tract.

Section 12: Ecological Information

Ecotoxicity: Not available.

BOD5 and COD: Not available.

Products of Biodegradation: Possibly hazardous short term degradation products are not likely. However, long term

degradation products may arise.

Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic.

Special Remarks on the Products of Biodegradation: Not available.

Section 13: Disposal Considerations

Waste Disposal:

Waste must be disposed of in accordance with federal, state and local environmental control regulations.

Section 14: Transport Information

DOT Classification: Class 8: Corrosive material

Identification: : Butyric Anhydride UNNA: 2739 PG: III

Special Provisions for Transport: Not available.

Section 15: Other Regulatory Information

Federal and State Regulations:

New Jersey: n-Butyric Anhydride TSCA 8(b) inventory: n-Butyric Anhydride TSCA 8(a) PAIR: n-Butyric Anhydride TSCA 8(d)

H and S data reporting: n-Butyric Anhydride: Effective data: 9/30/91; Sunset date: 12/19/95

Other Regulations:

OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). EINECS: This product is on the

European Inventory of Existing Commercial Chemical Substances.

Other Classifications:

WHMIS (Canada):

The WHMIS classification of this product has not yet been validated by the Serivce du repertoire toxicologique. It may be

classified as CLASS B-3: Combustible liquid with a flash point between 37.8°C (100°F) and 93.3°C (200°F) and CLASS E:

Corrosive liquid.

DSCL (EEC):

R34- Causes burns. S25- Avoid contact with eyes. S26- In case of contact with eyes, rinse immediately with plenty of water

and seek medical advice. S36/37/39- Wear suitable protective clothing, gloves and eye/face protection.

HMIS (U.S.A.):

Health Hazard: 3

Fire Hazard: 2

Reactivity: 1

Personal Protection:

National Fire Protection Association (U.S.A.):

Health: 3

Flammability: 2

Reactivity: 1

Specific hazard:

Protective Equipment:

Gloves. Full suit. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respirator

when ventilation is inadequate. Face shield.

Section 16: Other Information

References: Not available.

Other Special Considerations: Not available.

Created: 10/09/2005 04:28 PM

Last Updated: 11/06/2008 12:00 PM