Chloroacetyl Chloride For Synthesis MSDS

Chloroacetyl Chloride For Synthesis MSDS

 

Section 1: Chemical Product and Company Identification

Product Name: Chloroacetyl Chloride For Synthesis

Catalog Codes: SLC3508

CAS#: 79-04-9

RTECS: A06475000

TSCA: TSCA 8(b) inventory: Chloroacetyl Chloride

CI#: Not available.

Synonym:

Chemical Name: Not available.

Chemical Formula: C2-H2-Cl2-O

 

Section 2: Composition and Information on Ingredients

Composition:

Name CAS # % by Weight

Chloroacetyl Chloride 79-04-9 100

Toxicological Data on Ingredients: Chloroacetyl Chloride: ORAL (LD50): Acute: 220 mg/kg [Mouse]. 208 mg/kg [Rat].

DERMAL (LD50): Acute: 662 mg/kg [Rat].

 

Section 3: Hazards Identification

Potential Acute Health Effects:

Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation (lung irritant).

Corrosive to skin and eyes on contact. Liquid or spray mist may produce tissue damage particularly on mucous

membranes of eyes, mouth and respiratory tract. Skin contact may produce burns. Inhalation of the spray mist

may produce severe irritation of respiratory tract, characterized by coughing, choking, or shortness of breath.

Potential Chronic Health Effects:

CARCINOGENIC EFFECTS: Classified 4 (No evidence.) by NTP, None. by OSHA, None. by NIOSH.

MUTAGENIC EFFECTS: Not available.

TERATOGENIC EFFECTS: Not available.

DEVELOPMENTAL TOXICITY: Not available.

The substance may be toxic to eyes, central nervous system (CNS), ears, nose/sinuses, throat.

Repeated or prolonged exposure to the substance can produce target organs damage. Repeated or prolonged

contact with spray mist may produce chronic eye irritation and severe skin irritation. Repeated or prolonged

exposure to spray mist may produce respiratory tract irritation leading to frequent attacks of bronchial infection.

 

Section 4: First Aid Measures

Eye Contact:

Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at

least 15 minutes. Get medical attention immediately.

Skin Contact:

In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated

clothing and shoes. Cover the irritated skin with an emollient. Wash clothing before reuse. Thoroughly clean

shoes before reuse. Get medical attention immediately.

Serious Skin Contact:

Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate

medical attention.

Inhalation:

If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention immediately.

Serious Inhalation:

Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation.

WARNING: It may be hazardous to the person providing aid to give mouth-to-mouth resuscitation

when the inhaled material is toxic, infectious or corrosive. Seek immediate medical attention.

Ingestion:

Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband.

Serious Ingestion: Not available.

 

Section 5: Fire and Explosion Data

Flammability of the Product: May be combustible at high temperature.

Auto-Ignition Temperature: Not available.

Flash Points: Not available.

Flammable Limits: Not available.

Products of Combustion: These products are carbon oxides (CO, CO2), halogenated compounds.

Fire Hazards in Presence of Various Substances: Not available.

Explosion Hazards in Presence of Various Substances:

Risks of explosion of the product in presence of mechanical impact: Not available.

Risks of explosion of the product in presence of static discharge: Not available.

Fire Fighting Media and Instructions:

SMALL FIRE: Use DRY chemical powder.

LARGE FIRE: Use water spray, fog or foam. Do not use water jet.

Special Remarks on Fire Hazards: Not available.

Special Remarks on Explosion Hazards: Not available.

 

Section 6: Accidental Release Measures

Small Spill: Absorb with an inert material and put the spilled material in an appropriate waste disposal.

Large Spill:

Corrosive liquid.

Stop leak if without risk. Absorb with DRY earth, sand or other non-combustible material. Do not get water inside container. Do not touch spilled material. Use water spray curtain to divert vapor drift. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all ignition sources. Call for assistance on disposal. Be careful that the product is not present at a concentration level above TLV. Check TLV on the MSDS and with local authorities.

 

Section 7: Handling and Storage

Precautions:

Keep container dry. Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not breathe gas/fumes/ vapor/spray. Never add water to this product. Wear suitable protective clothing. If ingested, seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes. Keep away from incompatibles such as oxidizing agents, alkalis.

Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 25°C (77°F).

 

Section 8: Exposure Controls/Personal Protection

Engineering Controls:

Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station location.

Personal Protection:

Face shield. Full suit. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.

Boots.

Personal Protection in Case of a Large Spill:

Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.

Exposure Limits:

TWA: 0.05 STEL: 0.15 (ppm) from ACGIH (TLV) [United States] SKIN

TWA: 0.05 from NIOSH

TWA: 0.05 (ppm) [Denmark]

TWA: 0.05 (ppm) [United Kingdom (UK)]

Consult local authorities for acceptable exposure limits.

Section 9: Physical and Chemical Properties

Physical state and appearance: Liquid.

Odor: Pungent. (Strong.)

Taste: Not available.

Molecular Weight: 112.95 g/mole

Color: Colorless to light yellow.

pH (1% soln/water): Not available.

Boiling Point: 105°C (221°F)

Melting Point: -22°C (-7.6°F)

Critical Temperature: Not available.

Specific Gravity: Not available.

Vapor Pressure: 2.5 kPa (@ 20°C)

Vapor Density: 3.9 (Air = 1)

Volatility: Not available.

Odor Threshold: 0.011 ppm

Water/Oil Dist. Coeff.: Not available.

Ionicity (in Water): Not available.

Dispersion Properties:

Partially dispersed in diethyl ether.

See solubility in water, diethyl ether, acetone.

Solubility: Partially soluble in diethyl ether, acetone.

 

Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.

Conditions of Instability: Not available.

Incompatibility with various substances: Reactive with oxidizing agents, alkalis.

Corrosivity: Not available.

Special Remarks on Reactivity: Not available.

Special Remarks on Corrosivity: Not available.

Polymerization: Will not occur.

 

Section 11: Toxicological Information

Routes of Entry: Absorbed through skin. Eye contact. Inhalation. Ingestion.

Toxicity to Animals:

WARNING: THE LC50 VALUES HEREUNDER ARE ESTIMATED ON THE BASIS OF A 4-HOUR EXPOSURE.

Acute oral toxicity (LD50): 208 mg/kg [Rat].

Acute dermal toxicity (LD50): 662 mg/kg [Rat].

Acute toxicity of the gas (LC50): 1300 2 hours [Mouse].

Chronic Effects on Humans:

CARCINOGENIC EFFECTS: Classified 4 (No evidence.) by NTP, None. by OSHA, None. by NIOSH. May cause damage to the following organs: eyes, central nervous system (CNS), ears, nose/sinuses, throat.

Other Toxic Effects on Humans:

Hazardous in case of skin contact (corrosive, irritant), of eye contact (corrosive), of ingestion, of inhalation (lung irritant, lung corrosive).

Special Remarks on Toxicity to Animals: Not available.

Special Remarks on Chronic Effects on Humans: Not available.

Special Remarks on other Toxic Effects on Humans: Not available.

 

Section 12: Ecological Information

Ecotoxicity: Not available.

BOD5 and COD: Not available.

Products of Biodegradation:

Possibly hazardous short term degradation products are not likely. However, long term degradation products may

arise.

Toxicity of the Products of Biodegradation: The products of degradation are as toxic as the product itself.

Special Remarks on the Products of Biodegradation: Not available.

 

Section 13: Disposal Considerations

Waste Disposal:

 

Section 14: Transport Information

DOT Classification: CLASS 6.1: Poisonous material.

Identification: : Chloroacetyl Chloride, Poison Inhalation Hazard Zone B UNNA: 1752 PG: I

Special Provisions for Transport: Not available.

 

Section 15: Other Regulatory Information

Federal and State Regulations:

California prop. 65 (no significant risk level): Chloroacetyl Chloride

Rhode Island RTK hazardous substances: Chloroacetyl Chloride

Pennsylvania RTK: Chloroacetyl Chloride

Florida: Chloroacetyl Chloride

Minnesota: Chloroacetyl Chloride

Massachusetts RTK: Chloroacetyl Chloride

New Jersey: Chloroacetyl Chloride

TSCA 8(b) inventory: Chloroacetyl Chloride

Other Regulations:

OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).

EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.

Other Classifications:

WHMIS (Canada):

CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).

CLASS E: Corrosive liquid.

DSCL (EEC): R34- Causes burns.

HMIS (U.S.A.):

Health Hazard: 3

Fire Hazard: 1

Reactivity: 0

Personal Protection:

National Fire Protection Association (U.S.A.):

Health: 3

Flammability: 0

Reactivity: 1

Specific hazard:

Protective Equipment:

Gloves.

Full suit.

Vapor respirator. Be sure to use an

approved/certified respirator or

equivalent. Wear appropriate respirator

when ventilation is inadequate.

Face shield.

 

Section 16: Other Information

References: Not available.

Other Special Considerations: Not available.

Created: 10/09/2005 04:52 PM

Last Updated: 11/06/2008 12:00 PM