Coumarin For Synthesis MSDS

Coumarin For Synthesis MSDS

 

Section 1: Chemical Product and Company Identification

Product Name: Coumarin For Synthesis

Catalog Codes: SLC4390

CAS#: 91-64-5

RTECS: GN4200000

TSCA: TSCA 8(b) inventory: Coumarin

CI#: Not available.

Synonym: 2H-1-Benzopyran-2-one

Chemical Name: Coumarin

Chemical Formula: Not available.

 

Section 2: Composition and Information on Ingredients

Composition:

Name CAS # % by Weight

Coumarin 91-64-5 100

Toxicological Data on Ingredients: Coumarin: ORAL (LD50): Acute: 293 mg/kg [Rat]. 196 mg/kg [Mouse]. 202 mg/kg

[Guinea pig].

 

Section 3: Hazards Identification

Potential Acute Health Effects:

Extremely hazardous in case of ingestion. Hazardous in case of eye contact (irritant), of inhalation. Slightly

hazardous in case of skin contact (irritant). Severe over-exposure can result in death.

Potential Chronic Health Effects:

CARCINOGENIC EFFECTS: Classified 2B (Possible for human.) by IARC.

MUTAGENIC EFFECTS: Not available.

TERATOGENIC EFFECTS: Not available.

DEVELOPMENTAL TOXICITY: Not available.

Repeated exposure to an highly toxic material may produce general deterioration of health by an accumulation in

one or many human organs.

 

Section 4: First Aid Measures

Eye Contact:

Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes,

keeping eyelids open. Cold water may be used. Do not use an eye ointment. Seek medical attention.

Skin Contact:

After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin

with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin.

Cold water may be used. Cover the irritated skin with an emollient. If irritation persists, seek medical attention.

Wash contaminated clothing before reusing.

Serious Skin Contact: Not available.

Inhalation: Allow the victim to rest in a well ventilated area. Seek immediate medical attention.

Serious Inhalation:

Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or

waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth

resuscitation. Seek medical attention.

Ingestion:

Do not induce vomiting. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible

indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Loosen

tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth

resuscitation. Seek immediate medical attention.

Serious Ingestion: Not available.

 

Section 5: Fire and Explosion Data

Flammability of the Product: May be combustible at high temperature.

Auto-Ignition Temperature: Not available.

Flash Points: CLOSED CUP: 162°C (323.6°F).

Flammable Limits: Not available.

Products of Combustion: Not available.

Fire Hazards in Presence of Various Substances: Not available.

Explosion Hazards in Presence of Various Substances:

Risks of explosion of the product in presence of mechanical impact: Not available.

Risks of explosion of the product in presence of static discharge: Not available.

Fire Fighting Media and Instructions:

SMALL FIRE: Use DRY chemical powder.

LARGE FIRE: Use water spray, fog or foam. Do not use water jet.

Special Remarks on Fire Hazards: Not available.

Special Remarks on Explosion Hazards: Not available.

 

Section 6: Accidental Release Measures

Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container.

Large Spill: Use a shovel to put the material into a convenient waste disposal container.

 

Section 7: Handling and Storage

Precautions:

Keep locked up Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk,

evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not

breathe dust. Avoid contact with eyes Wear suitable protective clothing In case of insufficient ventilation, wear

suitable respiratory equipment If ingested, seek medical advice immediately and show the container or the label.

Storage:

Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly

closed. Keep in a cool, well-ventilated place. Highly toxic or infectious materials should be stored in a separate

locked safety storage cabinet or room.

 

Section 8: Exposure Controls/Personal Protection

Engineering Controls:

Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below

recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to

airborne contaminants below the exposure limit.

Personal Protection:

Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.

Gloves.

Personal Protection in Case of a Large Spill:

Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used

to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist

BEFORE handling this product.

Exposure Limits: Not available.

 

Section 9: Physical and Chemical Properties

Physical state and appearance: Solid.

Odor: Not available.

Taste: Not available.

Molecular Weight: 146.15 g/mole

Color: Not available.

pH (1% soln/water): Not available.

Boiling Point: 298°C (568.4°F)

Melting Point: 68°C (154.4°F)

Critical Temperature: Not available.

Specific Gravity: 0.935 (Water = 1)

Vapor Pressure: Not applicable.

Vapor Density: Not available.

Volatility: Not available.

Odor Threshold: Not available.

Water/Oil Dist. Coeff.: Not available.

Ionicity (in Water): Not available.

Dispersion Properties: See solubility in water.

Solubility: Partially soluble in cold water.

 

Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.

Conditions of Instability: Not available.

Incompatibility with various substances: Not available.

Corrosivity: Non-corrosive in presence of glass.

Special Remarks on Reactivity: Not available.

Special Remarks on Corrosivity: Not available.

Polymerization: No.

 

Section 11: Toxicological Information

Routes of Entry: Absorbed through skin. Eye contact. Inhalation. Ingestion.

Toxicity to Animals: Acute oral toxicity (LD50): 196 mg/kg [Mouse].

Chronic Effects on Humans: CARCINOGENIC EFFECTS: Classified 2B (Possible for human.) by IARC.

Other Toxic Effects on Humans:

Extremely hazardous in case of ingestion.

Hazardous in case of inhalation.

Slightly hazardous in case of skin contact (irritant).

Special Remarks on Toxicity to Animals: Not available.

Special Remarks on Chronic Effects on Humans: Not available.

Special Remarks on other Toxic Effects on Humans: Not available.

 

Section 12: Ecological Information

Ecotoxicity: Not available.

BOD5 and COD: Not available.

Products of Biodegradation:

Possibly hazardous short term degradation products are not likely. However, long term degradation products may

arise.

Toxicity of the Products of Biodegradation: The products of degradation are more toxic.

Special Remarks on the Products of Biodegradation: Not available.

 

Section 13: Disposal Considerations

Waste Disposal:

 

Section 14: Transport Information

DOT Classification:

Identification:

Special Provisions for Transport: Not available.

Section 15: Other Regulatory Information

Federal and State Regulations: TSCA 8(b) inventory: Coumarin

Other Regulations: OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).

Other Classifications:

WHMIS (Canada):

CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC).

CLASS D-2A: Material causing other toxic effects (VERY TOXIC).

DSCL (EEC):

R22- Harmful if swallowed.

R36- Irritating to eyes.

R40- Possible risks of irreversible

effects.

HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 1

Reactivity: 0

Personal Protection: E

National Fire Protection Association (U.S.A.):

Health: 2

Flammability: 1

Reactivity: 0

Specific hazard:

Protective Equipment:

Gloves.

Lab coat.

Dust respirator. Be sure to use an

approved/certified respirator or

equivalent. Wear appropriate respirator

when ventilation is inadequate.

Splash goggles.

 

Section 16: Other Information

References: Not available.

Other Special Considerations: Not available.

Created: 10/09/2005 04:59 PM

Last Updated: 11/06/2008 12:00 PM