Synonyms: Butanedioic acid, hydroxy-; hydroxysuccinic acid; hydroxybutanedioic acid
CAS No.: 617-48-1 (dl form)
Molecular Weight: 134.09
Chemical Formula: C4H6O5
Product Codes: 4940, P494
Ingredient CAS No Percent Hazardous --------------------------------------- ------------ ------------ --------- dl-Malic Acid 617-48-1 100% Yes
Emergency Overview
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WARNING! CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT. MAY BE HARMFUL IF SWALLOWED.
SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 1 - Slight
Flammability Rating: 1 - Slight
Reactivity Rating: 0 - None
Contact Rating: 3 - Severe
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER GLOVES
Storage Color Code: Green (General Storage)
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Potential Health Effects
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Information on the human health effects from exposure to this substance is limited.
Inhalation:
Inhalation of dust is irritating to the upper respiratory tract.
Ingestion:
Moderately toxic by ingestion based on LD50 data.
Skin Contact:
Causes moderate skin irritation based on Draize information for rabbits.
Eye Contact:
Causes severe eye irritation based on Draize information for rabbits.
Chronic Exposure:
No information found.
Aggravation of Pre-existing Conditions:
No information found.
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.
Ingestion:
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact:
Remove any contaminated clothing. Wash skin with soap or mild detergent and water for at least 15 minutes. Get medical attention if irritation develops or persists.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
Fire:
As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source.
Explosion:
Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.
Fire Extinguishing Media:
Water spray, dry chemical, alcohol foam, or carbon dioxide.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
Remove all sources of ignition. Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Spills: Clean up spills in a manner that does not disperse dust into the air. Use non-sparking tools and equipment. Reduce airborne dust and prevent scattering by moistening with water. Pick up spill for recovery or disposal and place in a closed container.
Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Isolate from incompatible substances. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.
Airborne Exposure Limits:
None established.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn. If oil particles (e.g. lubricants, cutting fluids, glycerine, etc.) are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear protective gloves and clean body-covering clothing.
Eye Protection:
Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.
Appearance:
White or colorless crystals.
Odor:
Odorless.
Solubility:
Soluble in water.
Specific Gravity:
1.601
pH:
No information found.
% Volatiles by volume @ 21C (70F):
0
Boiling Point:
150C (302F) Decomposes.
Melting Point:
131 - 133C (268 - 271F)
Vapor Density (Air=1):
No information found.
Vapor Pressure (mm Hg):
No information found.
Evaporation Rate (BuAc=1):
No information found.
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Oxidizing agents, bases, alkali metals and amines.
Conditions to Avoid:
Heat and incompatibles.
LD50 oral mouse: 1600mg/kg
Standard Draize/rabbit skin: 500mg/24H, moderate;
rabbit eye: 750ug/24H, severe.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
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dl-Malic Acid (617-48-1) No No None
Environmental Fate:
When released into the air, this material is expected to be readily degraded by reaction with photochemically produced hydroxyl radicals. When released into the soil, this material is expected to readily biodegrade. When released into water, this material is expected to readily biodegrade. This material is not expected to significantly bioaccumulate.
Environmental Toxicity:
No information found.
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.
Not regulated.
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
dl-Malic Acid (617-48-1) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
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dl-Malic Acid (617-48-1) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
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dl-Malic Acid (617-48-1) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
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dl-Malic Acid (617-48-1) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: No Fire: No Pressure: No
Reactivity: No (Mixture / Solid)
Australian Hazchem Code: None allocated.
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.
NFPA Ratings: Health: 1 Flammability: 1 Reactivity: 0
Label Hazard Warning:
WARNING! CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT. MAY BE HARMFUL IF SWALLOWED.
Label Precautions:
Do not breathe dust.
Do not get in eyes, on skin, or on clothing.
Keep container closed.
Use with adequate ventilation.
Wash thoroughly after handling.
Label First Aid:
In case of eye contact, immediately flush eyes with plenty of water for at least 15 minutes. Call a physician. In case of contact, immediately flush skin with plenty of water for at least 15 minutes. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. If swallowed, call a physician immediately.
Product Use:
Laboratory Reagent.
Revision Information:
No Changes.
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Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)