Synonyms: Manna Sugar; Mannite; Mannitol,d- ; 1,2,3,4,5,6-Hexanehexol
CAS No.: 69-65-8
Molecular Weight: 182.17
Chemical Formula: C6H14O6
Product Codes:
J.T. Baker: 2553, 2554, 2555
Mallinckrodt: 6208, 6209, 6212, 7781
Ingredient CAS No Percent Hazardous --------------------------------------- ------------ ------------ --------- D-Mannitol 69-65-8 90 - 100% Yes
Emergency Overview
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WARNING! MAY FORM COMBUSTIBLE DUST CONCENTRATIONS IN AIR.
SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 0 - None
Flammability Rating: 2 - Moderate
Reactivity Rating: 0 - None
Contact Rating: 1 - Slight
Lab Protective Equip: GOGGLES; LAB COAT
Storage Color Code: Green (General Storage)
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Potential Health Effects
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Inhalation:
Large quantities of inhaled material could cause irritation of the upper respiratory tract. A tickling cough is a common symptom.
Ingestion:
May cause gastric irritation, nausea and diarrhea. Large doses produce vomiting, chills, dizziness, chest pain, heart failure and pulmonary edema.
Skin Contact:
May cause irritation and discoloration of sensitive skin areas.
Eye Contact:
May cause irritation, redness and pain.
Chronic Exposure:
No information found.
Aggravation of Pre-existing Conditions:
No information found.
Inhalation:
Remove to fresh air. Get medical attention for any breathing difficulty.
Ingestion:
If large amounts were swallowed, give water to drink and get medical advice.
Skin Contact:
Wash exposed area with soap and water. Get medical advice if irritation develops.
Eye Contact:
Wash thoroughly with running water. Get medical advice if irritation develops.
Fire:
As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source. Mannitol: Flash Point: > 149C (300F)
Minimum dust cloud ignition temperature: 460C (860F)
Explosion:
Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard. Mannitol: Minimum explosible concentration = 0.065 g/l; Maximum explosion pressure: 97 lb/sq. in.
Fire Extinguishing Media:
Water spray, carbon dioxide, or dry powder.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. Pressure from the extinguishing media may cause severe dusting.
Remove all sources of ignition. Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Spills: Clean up spills in a manner that does not disperse dust into the air. Use non-sparking tools and equipment. Reduce airborne dust and prevent scattering by moistening with water. Pick up spill for recovery or disposal and place in a closed container.
Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Isolate from any source of heat or ignition. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.
Airborne Exposure Limits:
None established.
Ventilation System:
In general, dilution ventilation is a satisfactory health hazard control for this substance. However, if conditions of use create discomfort to the worker, a local exhaust system should be considered.
Personal Respirators (NIOSH Approved):
For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn. If oil particles (e.g. lubricants, cutting fluids, glycerine, etc.) are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear protective gloves and clean body-covering clothing.
Eye Protection:
Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.
Appearance:
White powder.
Odor:
Odorless.
Solubility:
1 gram/5.5 ml of water.
Relative Density:
1.52
pH:
No information found.
% Volatiles by volume @ 21C (70F):
0
Boiling Point:
290 - 295C (554 - 563F)
Melting Point:
ca. 167C (ca. 333F)
Vapor Density (Air=1):
No information found.
Vapor Pressure (mm Hg):
No information found.
Evaporation Rate (BuAc=1):
No information found.
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizers.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.
Mannitol: Oral rat LD50: 13,500 mg/kg. Investigated as a tumorigen and mutagen.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
D-Mannitol (69-65-8) No No None
Environmental Fate:
No information found.
Environmental Toxicity:
No information found.
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.
Not regulated.
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
D-Mannitol (69-65-8) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
D-Mannitol (69-65-8) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
D-Mannitol (69-65-8) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
D-Mannitol (69-65-8) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: No Chronic: No Fire: Yes Pressure: No
Reactivity: No (Pure / Solid)
Australian Hazchem Code: None allocated.
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.
NFPA Ratings: Health: 1 Flammability: 1 Reactivity: 0
Label Hazard Warning:
WARNING! MAY FORM COMBUSTIBLE DUST CONCENTRATIONS IN AIR.
Label Precautions:
Store in a tightly closed container.
Avoid dust cloud in presence of an ignition source.
Maintain adequate ventilation.
Label First Aid:
Not applicable.
Product Use:
Laboratory Reagent.
Revision Information:
No Changes.
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Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)