Synonyms: o-Methoxyphenol; Methylcatechol; 2-Methoxyphenol
CAS No.: 90-05-1
Molecular Weight: 124.14
Chemical Formula: CH3OC6H4OH
Product Codes: M840
Ingredient CAS No Percent Hazardous --------------------------------------- ------------ ------------ --------- Guaiacol 90-05-1 98% Yes
Emergency Overview
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WARNING! CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT. MAY BE HARMFUL IF SWALLOWED OR ABSORBED THROUGH SKIN. COMBUSTIBLE LIQUID AND VAPOR.
SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 2 - Moderate
Flammability Rating: 2 - Moderate
Reactivity Rating: 1 - Slight
Contact Rating: 2 - Moderate (Life)
Lab Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES; CLASS B EXTINGUISHER
Storage Color Code: Red (Flammable)
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Potential Health Effects
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Inhalation:
May cause irritation to the respiratory tract.
Ingestion:
Causes irritation to the gastrointestinal tract. Symptoms may include nausea, vomiting and diarrhea. May cause mild burning of mouth, throat, and stomach. May cause muscular weakness, paralysis of the vasomotor centers and possible cardiovascular or respiratory collapse.
Skin Contact:
Brief contact may have no effect. Prolonged or repeated contact may cause irritation, redness, itching and pain. Can be absorbed through the skin quite readily with possible systemic effects.
Eye Contact:
Causes irritation, redness, and pain.
Chronic Exposure:
No information found.
Aggravation of Pre-existing Conditions:
No information found.
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion:
Do NOT induce vomiting. Give large amounts of water. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
Fire:
Flash point: 82C (180F) CC
Combustible Liquid and Vapor!
Contact with strong oxidizers may cause fire.
Explosion:
Vapors can flow along surfaces to distant ignition source and flash back. Sealed containers may rupture when heated.
Fire Extinguishing Media:
Water, dry chemical, foam or carbon dioxide. Water spray may be used to keep fire exposed containers cool. Move exposed containers from fire area, if it can be done without risk.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from entering. Contain and recover liquid when possible. Use non-sparking tools and equipment. Collect liquid in an appropriate container or absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Do not use combustible materials, such as saw dust. Do not flush to sewer!
J. T. Baker SOLUSORB® solvent adsorbent is recommended for spills of this product.
Keep in a tightly closed container. Store in a cool, dry, ventilated area away from sources of heat or ignition. Protect against physical damage. Store separately from reactive or combustible materials, and out of direct sunlight. Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed for the product.
Airborne Exposure Limits:
None established.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
For conditions of use where exposure to the substance is apparent and engineering controls are not feasble, consult an industrial hygienist. For emergencies, or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Appearance:
Colorless to yellow, refractive liquid.
Odor:
Slight phenolic odor.
Solubility:
Moderate solubility in water.
Density:
ca. 1.112
pH:
No information found.
% Volatiles by volume @ 21C (70F):
N/A
Boiling Point:
205C (401F)
Melting Point:
28C (82F) (solidifies)
Vapor Density (Air=1):
4.3
Vapor Pressure (mm Hg):
0.103 @ 25C (77F)
Evaporation Rate (BuAc=1):
No information found.
Stability:
Stable under ordinary conditions of use and storage. Darkens on exposure to air or light.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Acid chlorides and acid anhydrides. May react with oxidizing materials. Forms salts readily with bases.
Conditions to Avoid:
Heat, flame, ignition sources, air, light and incompatibles.
For Guaiacol: Acute Toxicity: rat, oral LD50 dose 520 mg/kg; rabbit, skin LD50 dose 4600 mg/kg; investigated as a mutagen. Irritation Data (Std Draize, rabbit): skin, 500 mg/24H, severe; eye, 5 mg, mild.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Guaiacol (90-05-1) No No None
Environmental Fate:
When released into the soil, this material may biodegrade to a moderate extent. When released into the soil, this material is expected to leach into groundwater. When released into water, this material is not expected to evaporate significantly. When released into water, this material may biodegrade to a moderate extent. This material is not expected to significantly bioaccumulate. When released into the air, this material is expected to be readily degraded by reaction with photochemically produced hydroxyl radicals. When released into the air, this material may be removed from the atmosphere to a moderate extent by wet deposition.
Environmental Toxicity:
No information found.
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.
Not regulated.
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Guaiacol (90-05-1) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Guaiacol (90-05-1) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Guaiacol (90-05-1) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Guaiacol (90-05-1) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: No Fire: Yes Pressure: No
Reactivity: No (Pure / Liquid)
Australian Hazchem Code: None allocated.
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.
NFPA Ratings: Health: 1 Flammability: 2 Reactivity: 1
Label Hazard Warning:
WARNING! CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT. MAY BE HARMFUL IF SWALLOWED OR ABSORBED THROUGH SKIN. COMBUSTIBLE LIQUID AND VAPOR.
Label Precautions:
Avoid contact with eyes, skin and clothing.
Wash thoroughly after handling.
Avoid breathing vapor or mist.
Keep container closed.
Use only with adequate ventilation.
Keep away from heat and flame.
Label First Aid:
In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never give anything by mouth to an unconscious person. In all cases, get medical attention.
Product Use:
Laboratory Reagent.
Revision Information:
No Changes.
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Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)