Synonyms: Phenol, p-methoxy; hydroquinone monomethyl ether; p-Hydroxyanisole
CAS No.: 150-76-5
Molecular Weight: 124.14
Chemical Formula: C7H8O2
Product Codes: P886
Ingredient CAS No Percent Hazardous --------------------------------------- ------------ ------------ --------- 4-Methoxyphenol 150-76-5 100% Yes
Emergency Overview
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WARNING! HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT. MAY AFFECT CENTRAL NERVOUS SYSTEM.
SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 2 - Moderate (Life)
Flammability Rating: 1 - Slight
Reactivity Rating: 0 - None
Contact Rating: 3 - Severe
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER GLOVES
Storage Color Code: Green (General Storage)
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Potential Health Effects
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Inhalation:
Inhalation can cause irritation of mucous membranes and upper respiratory tract. Symptoms may include burning sensation, coughing, wheezing, laryngitis, shortness of breath, sore throat, bronchitis, pneumonitis, and possible pulmonary edema.
Ingestion:
Moderately toxic by ingestion. Causes irritation to the gastrointestinal tract. Symptoms may include nausea, vomiting, diarrhea, lowered blood pressure and cardiac arrhythmias. May cause central nervous system depression and possibly coma. Ingesting a > 5% solution may cause oral burns; ingesting 1g can cause death.
Skin Contact:
Causes irritation. Symptoms include redness, itching and pain. Skin may become ulcerated. Prolonged skin contact can cause burns, dermatitis and discoloration of the skin. May be absorbed through the skin. Symptoms may parallel those from ingestion exposure.
Eye Contact:
Causes irritation and may cause lesions that can lead to corneal erosion, partial or total vision loss. May also cause keratitis and discoloration of the conjunctiva.
Chronic Exposure:
No information found.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin or eye disorders or impaired respiratory function may be more susceptible to the effects of this substance.
Inhalation:
Remove to fresh air. Get medical attention for any breathing difficulty.
Ingestion:
If swallowed, DO NOT INDUCE VOMITING. Get immediate medical attention. Never give anything by mouth to an unconscious person. Avoid dilution since this may enhance phenol absorption.
Skin Contact:
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
Fire:
Flash point: 124C (255F) CC
Autoignition temperature: 421C (790F)
May pose a fire hazard when exposed to heat, flame, or oxidizing agents.
Explosion:
Not considered to be an explosion hazard.
Fire Extinguishing Media:
Water, carbon dioxide, or dry chemical.
Special Information:
Wear full protective clothing and breathing equipment for high-intensity fire or potential explosion conditions.
Remove all sources of ignition. Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Spills: Clean up spills in a manner that does not disperse dust into the air. Use non-sparking tools and equipment. Reduce airborne dust and prevent scattering by moistening with water. Pick up spill for recovery or disposal and place in a closed container.
Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Isolate from any source of heat or ignition. Isolate from oxidizing materials. Protect from direct sunlight. Protect against moisture and air. Store at temperatures not exceeding 230C (110F) for any extended time since sintering (heat-induced cohering without melting) can occur.
Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.
Airborne Exposure Limits:
- ACGIH Threshold Limit Value (TLV): 5 mg/m3 (TWA)
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded and engineering controls are not feasible, a full facepiece particulate respirator (NIOSH type N100 filters) may be worn for up to 50 times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. If oil particles (e.g. lubricants, cutting fluids. glycerine, etc.) are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Appearance:
White waxy solid.
Odor:
No information found.
Solubility:
Soluble in water.
Specific Gravity:
1.55 @ 20C
pH:
No information found.
% Volatiles by volume @ 21C (70F):
0
Boiling Point:
243C (469F)
Melting Point:
57C (135F)
Vapor Density (Air=1):
4.29
Vapor Pressure (mm Hg):
19 @ 140C (284F)
Evaporation Rate (BuAc=1):
No information found.
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Carbon monoxide.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Sodium hydroxide and oxidizing agents.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.
No LD50/LC50 information found relating to normal routes of occupational exposure. Irritation skin rabbit (std Draize): 6 gm/12D-I, mild. Investigated as a mutagen.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
4-Methoxyphenol (150-76-5) No No None
Environmental Fate:
No information found.
Environmental Toxicity:
No information found.
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.
Not regulated.
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
4-Methoxyphenol (150-76-5) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
4-Methoxyphenol (150-76-5) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
4-Methoxyphenol (150-76-5) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
4-Methoxyphenol (150-76-5) No No Yes
Chemical Weapons Convention: No TSCA 12(b): Yes CDTA: No
SARA 311/312: Acute: Yes Chronic: No Fire: No Pressure: No
Reactivity: No (Pure / Solid)
Australian Hazchem Code: None allocated.
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.
NFPA Ratings: Health: 1 Flammability: 1 Reactivity: 0
Label Hazard Warning:
WARNING! HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT. MAY AFFECT CENTRAL NERVOUS SYSTEM.
Label Precautions:
Avoid breathing dust or vapors.
Avoid contact with eyes, skin and clothing.
Keep container closed.
Use only with adequate ventilation.
Wash thoroughly after handling.
Label First Aid:
If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never give anything by mouth to an unconscious person. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. In all cases, get medical attention.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(s) changed since last revision of document include: 3.
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Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)