n-Chlorosuccinimide For Synthesis MSDS

Section 1: Chemical Product and Company Identification

Product Name: n-Chlorosuccinimide For Synthesis

Catalog Codes: SLC4234

CAS#: 128-09-6

RTECS: UY1013500

TSCA: TSCA 8(b) inventory: n-Chlorosuccinimide For Synthesis

CI#: Not available.

Synonym: 1-Chloro-2,5-pyrrolidinedione;

Succinochlorimide

Chemical Name: n-Chlorosuccinimide

Chemical Formula: C4-H4-Cl-N-O2

Section 2: Composition and Information on Ingredients

Composition:

Name CAS # % by Weight

{n-}Chlorosuccinimide For Synthesis 128-09-6 100

Toxicological Data on Ingredients: n-Chlorosuccinimide: ORAL (LD50): Acute: 1000 mg/kg [Rat].

Section 3: Hazards Identification

Potential Acute Health Effects:

Very hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Slightly

hazardous in case of skin contact (corrosive), of eye contact (corrosive). The amount of tissue damage depends

on length of contact. Eye contact can result in corneal damage or blindness. Skin contact can produce

inflammation and blistering. Inhalation of dust will produce irritation to gastro-intestinal or respiratory tract,

characterized by burning, sneezing and coughing. Severe over-exposure can produce lung damage, choking,

unconsciousness or death. Inflammation of the eye is characterized by redness, watering, and itching. Skin

inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering.

Potential Chronic Health Effects:

CARCINOGENIC EFFECTS: Not available.

MUTAGENIC EFFECTS: Not available.

TERATOGENIC EFFECTS: Not available.

DEVELOPMENTAL TOXICITY: Not available.

Repeated exposure of the eyes to a low level of dust can produce eye irritation. Repeated skin exposure can

produce local skin destruction, or dermatitis. Repeated inhalation of dust can produce varying degree of

respiratory irritation or lung damage.

Section 4: First Aid Measures

Eye Contact:

Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at

least 15 minutes. Cold water may be used. Get medical attention immediately.

Skin Contact:

In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated

clothing and shoes. Cover the irritated skin with an emollient. Cold water may be used.Wash clothing before

reuse. Thoroughly clean shoes before reuse. Get medical attention immediately.

Serious Skin Contact:

Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate

medical attention.

Inhalation:

If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get

medical attention.

Serious Inhalation:

Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or

waistband. WARNING: It may be hazardous to the person providing aid to give mouth-to-mouth resuscitation

when the inhaled material is toxic, infectious or corrosive. Seek immediate medical attention.

Ingestion:

Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an

unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight

clothing such as a collar, tie, belt or waistband.

Serious Ingestion: Not available.

Section 5: Fire and Explosion Data

Flammability of the Product: May be combustible at high temperature.

Auto-Ignition Temperature: Not available.

Flash Points: Not available.

Flammable Limits: Not available.

Products of Combustion: These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), halogenated

compounds.

Fire Hazards in Presence of Various Substances:

Slightly flammable to flammable in presence of open flames and sparks, of heat.

Non-flammable in presence of shocks.

Explosion Hazards in Presence of Various Substances:

Risks of explosion of the product in presence of mechanical impact: Not available.

Risks of explosion of the product in presence of static discharge: Not available.

Fire Fighting Media and Instructions:

SMALL FIRE: Use DRY chemical powder.

LARGE FIRE: Use water spray, fog or foam. Do not use water jet.

Special Remarks on Fire Hazards: Not available.

Special Remarks on Explosion Hazards: Explosive reaction with aliphatic alcohols, benzylamine, and hydrazine hydrate.

Section 6: Accidental Release Measures

Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container.

Large Spill:

Corrosive solid.

Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray to

reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all ignition

sources. Call for assistance on disposal.

Section 7: Handling and Storage

Precautions:

Keep container dry. Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire

risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not ingest. Do not

breathe dust. Never add water to this product. In case of insufficient ventilation, wear suitable respiratory

equipment. If ingested, seek medical advice immediately and show the container or the label. Avoid contact with

skin and eyes. Keep away from incompatibles such as oxidizing agents, acids, alkalis.

Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 5°C (41°F).

Section 8: Exposure Controls/Personal Protection

Engineering Controls:

Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below

recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to

airborne contaminants below the exposure limit.

Personal Protection:

Splash goggles. Synthetic apron. Vapor and dust respirator. Be sure to use an approved/certified respirator or

equivalent. Gloves.

Personal Protection in Case of a Large Spill:

Splash goggles. Full suit. Vapor and dust respirator. Boots. Gloves. A self contained breathing apparatus

should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a

specialist BEFORE handling this product.

Exposure Limits: Not available.

Section 9: Physical and Chemical Properties

Physical state and appearance: Solid. (crystalline powder.)

Odor: Chlorine

Taste: Not available.

Molecular Weight: 133.53 g/mole

Color: White.

pH (1% soln/water): Not available.

Boiling Point: 216.5°C (421.7°F)

Melting Point: 150°C (302°F)

Critical Temperature: Not available.

Specific Gravity: 1.65 (Water = 1)

Vapor Pressure: Not applicable.

Vapor Density: Not available.

Volatility: Not available.

Odor Threshold: Not available.

Water/Oil Dist. Coeff.: Not available.

Ionicity (in Water): Not available.

Dispersion Properties: See solubility in water, acetone.

Solubility:

Soluble in acetone.

Partially soluble in cold water.

Very slightly soluble in diethyl ether.

Slightly soluble in alcohol, acetic acid, and petroleum ether.

Sparingly soluble in chloroform, and carbon tetrachloride

Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.

Conditions of Instability: Excess heat, dust generation, incompatible materials, exposure to moist air or water, exposure to

light.

Incompatibility with various substances: Reactive with oxidizing agents, acids, alkalis.

Corrosivity: Not available.

Special Remarks on Reactivity: Also incompatible with amines, ammonia, iron, and iron salts.

Special Remarks on Corrosivity: Not available.

Polymerization: Will not occur.

Section 11: Toxicological Information

Routes of Entry: Inhalation. Ingestion.

Toxicity to Animals: Acute oral toxicity (LD50): 1000 mg/kg [Rat].

Chronic Effects on Humans: Not available.

Other Toxic Effects on Humans:

Very hazardous in case of skin contact (irritant), of ingestion, of inhalation.

Slightly hazardous in case of skin contact (corrosive), of eye contact (corrosive).

Special Remarks on Toxicity to Animals: Not available.

Special Remarks on Chronic Effects on Humans: May cause cancer (tumorigenic) based on animal data

Special Remarks on other Toxic Effects on Humans:

Acute Potential Health Effects:

Skin: May cause severe irritation with possible burns.

Eyes: May cause severe irritaiton and possible burns.

Inhalation: May cause irritation of the respiratory with burning pain in th enose and throat, coughing, wheezing,

shortness of breath, dyspnea, and pulmonary edema, and edema of the larynx.

Ingestion: May be harmful if swallowed. May casue severe gastrointestinal (digestive) tract irritation with nausea,

vomiting, pain and inflammation of the mouth, pharynx, esophagus, and stomach, and possible burns (erosion of

the mucous membranes, chiefly of the stomach). May affect behavior (confusion, delirium, food intake),

metabolism, and blood.

Section 12: Ecological Information

Ecotoxicity: Not available.

BOD5 and COD: Not available.

Products of Biodegradation:

Possibly hazardous short term degradation products are not likely. However, long term degradation products may

arise.

Toxicity of the Products of Biodegradation: The products of degradation are as toxic as the product itself.

Special Remarks on the Products of Biodegradation: Not available.

Section 13: Disposal Considerations

Waste Disposal:

Waste must be disposed of in accordance with federal, state and local environmental

control regulations.

Section 14: Transport Information

DOT Classification: Class 8: Corrosive material

Identification: : Corrosive Solid, Acidic, Organic, n.o.s. (n-Chlorosuccinimide) UNNA: 3261 PG: III

Special Provisions for Transport: Not available.

Section 15: Other Regulatory Information

Federal and State Regulations: TSCA 8(b) inventory: n-Chlorosuccinimide

Other Regulations:

OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).

EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.

Other Classifications:

WHMIS (Canada): Not controlled under WHMIS (Canada).

DSCL (EEC):

R22- Harmful if swallowed.

R38- Irritating to skin.

R41- Risk of serious damage to eyes.

S2- Keep out of the reach of children.

S26- In case of contact with eyes, rinse

immediately with plenty of water and seek

medical advice.

S39- Wear eye/face protection.

S46- If swallowed, seek medical advice

immediately and show this container or label.

HMIS (U.S.A.):

Health Hazard: 3

Fire Hazard: 1

Reactivity: 0

Personal Protection: j

National Fire Protection Association (U.S.A.):

Health: 3

Flammability: 1

Reactivity: 0

Specific hazard:

Protective Equipment:

Gloves.

Synthetic apron.

Vapor and dust respirator. Be sure to

use an approved/certified respirator or

equivalent.

Splash goggles.

Section 16: Other Information

References: Not available.

Other Special Considerations: Not available.

Created: 10/09/2005 04:54 PM

Last Updated: 11/06/2008 12:00 PM