o-Toluidine AR MSDS

o-Toluidine AR MSDS

 

Section 1: Chemical Product and Company Identification

Product Name: o-Toluidine AR

Catalog Codes: SLT2809

CAS#: 95-53-4

RTECS: XU2975000

TSCA: TSCA 8(b) inventory: o-Toluidine AR

CI#: Not applicable.

Synonym: 2-Aminotoluene

Chemical Name: 2-Methyl-1-aminobenzene

Chemical Formula: CH3C6H4NH2

 

Section 2: Composition and Information on Ingredients

Composition:

Name CAS # % by Weight

{ortho-}Toluidine 95-53-4 100

Toxicological Data on Ingredients: ortho-Toluidine: ORAL (LD50): Acute: 670 mg/kg [Rat.]. DERMAL (LD50): Acute: 3245

mg/kg [Rabbit.].

 

Section 3: Hazards Identification

Potential Acute Health Effects:

Very hazardous in case of skin contact (permeator), of ingestion, of inhalation. Hazardous in case of skin contact

(irritant), of eye contact (irritant).

Potential Chronic Health Effects:

Very hazardous in case of eye contact (irritant).

CARCINOGENIC EFFECTS: Classified + (PROVEN) by OSHA. Classified 2B (Possible for human.) by IARC.

Classified A2 (Suspected for human.) by ACGIH, 2 (Reasonably anticipated.) by NTP.

MUTAGENIC EFFECTS: Classified SUSPECTED for human.

TERATOGENIC EFFECTS: Not available.

DEVELOPMENTAL TOXICITY: PROVEN

The substance is toxic to blood, kidneys, the nervous system, the reproductive system, liver, mucous

membranes.

Repeated or prolonged exposure to the substance can produce target organs damage.

 

Section 4: First Aid Measures

Eye Contact:

Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes,

keeping eyelids open. Finish by rinsing thoroughly with running water to avoid a possible infection. Cold water

may be used.

Skin Contact:

After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin

with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin.

Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminated

clothing before reusing.

Serious Skin Contact:

Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek immediate

medical attention.

Inhalation: Allow the victim to rest in a well ventilated area. Seek immediate medical attention.

Serious Inhalation:

Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or

waistband. If breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth

resuscitation. Seek medical attention.

Ingestion:

Do not induce vomiting. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible

indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Loosen

tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth

resuscitation. Seek immediate medical attention.

Serious Ingestion: Not available.

 

Section 5: Fire and Explosion Data

Flammability of the Product: Combustible.

Auto-Ignition Temperature: 481.67°C (899°F)

Flash Points: CLOSED CUP: 85°C (185°F).

Flammable Limits: LOWER: 1.5%

Products of Combustion: These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...).

Fire Hazards in Presence of Various Substances:

Highly flammable in presence of open flames and sparks, of heat.

Flammable in presence of moisture.

Explosion Hazards in Presence of Various Substances:

Risks of explosion of the product in presence of mechanical impact: Not available.

Risks of explosion of the product in presence of static discharge: Not available.

Fire Fighting Media and Instructions:

SMALL FIRE: Use DRY chemical powder.

LARGE FIRE: Use water spray, fog or foam. Do not use water jet.

Special Remarks on Fire Hazards: Store under nitrogen.

Special Remarks on Explosion Hazards: Not available.

 

Section 6: Accidental Release Measures

Small Spill: Absorb with an inert material and put the spilled material in an appropriate waste disposal.

Large Spill:

Combustible material.

Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Be careful that the product

is not present at a concentration level above TLV. Check TLV on the MSDS and with local authorities.

 

Section 7: Handling and Storage

Precautions:

Keep locked up Keep away from heat. Keep away from sources of ignition. Ground all equipment containing

material. Do not ingest. Do not breathe gas/fumes/ vapour/spray. Wear suitable protective clothing In case of

insufficient ventilation, wear suitable respiratory equipment If ingested, seek medical advice immediately and

show the container or the label. Avoid contact with skin and eyes Keep away from incompatibles such as

oxidizing agents, acids.

Storage:

Alkalis may be stored in heavy duty gauge steel containers. Flammable materials should be stored in a separate

safety storage cabinet or room. Keep away from heat. Keep away from sources of ignition. Keep container

tightly closed. Keep in a cool, well-ventilated place. Ground all equipment containing material. Keep container

dry. Keep in a cool place.

 

Section 8: Exposure Controls/Personal Protection

Engineering Controls:

Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors below their

respective threshold limit value. Ensure that eyewash stations and safety showers are proximal to the

work-station location.

Personal Protection:

Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent.

Gloves.

Personal Protection in Case of a Large Spill:

Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be

used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist

BEFORE handling this product.

Exposure Limits:

TWA: 2 (ppm) from ACGIH (TLV) [1995]

TWA: 8.8 (mg/m3) from ACGIH [1995]Consult local authorities for acceptable exposure limits.

 

Section 9: Physical and Chemical Properties

Physical state and appearance: Liquid. (Liquid.)

Odor: Not available.

Taste: Not available.

Molecular Weight: 107.15 g/mole

Color: Colorless to light yellow.

pH (1% soln/water): 9 [Basic.]

Boiling Point: 200.2°C (392.4°F)

Melting Point: -14.7°C (5.5°F)

Critical Temperature: Not available.

Specific Gravity: 1 (Water = 1)

Vapor Pressure: 0.26 mm of Hg (@ 20°C)

Vapor Density: 3.69 (Air = 1)

Volatility: Not available.

Odor Threshold: Not available.

Water/Oil Dist. Coeff.: Not available.

Ionicity (in Water): Not available.

Dispersion Properties: See solubility in water, methanol, diethyl ether.

Solubility:

Soluble in methanol, diethyl ether.

Very slightly soluble in cold water, hot water.

 

Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.

Conditions of Instability: Not available.

Incompatibility with various substances: Reactive with oxidizing agents, acids.

Corrosivity: Non-corrosive in presence of glass.

Special Remarks on Reactivity: Air and light sensitive.

Special Remarks on Corrosivity: Not available.

Polymerization: No.

 

Section 11: Toxicological Information

Routes of Entry: Dermal contact. Eye contact. Inhalation. Ingestion.

Toxicity to Animals:

Acute oral toxicity (LD50): 670 mg/kg [Rat.].

Acute dermal toxicity (LD50): 3245 mg/kg [Rabbit.].

Chronic Effects on Humans:

CARCINOGENIC EFFECTS: Classified + (PROVEN) by OSHA. Classified 2B (Possible for human.) by IARC.

Classified A2 (Suspected for human.) by ACGIH, 2 (Reasonably anticipated.) by NTP.

MUTAGENIC EFFECTS: Classified SUSPECTED for human.

DEVELOPMENTAL TOXICITY: PROVEN

The substance is toxic to blood, kidneys, the nervous system, the reproductive system, liver, mucous

membranes.

Other Toxic Effects on Humans:

Very hazardous in case of skin contact (permeator), of ingestion, of inhalation.

Hazardous in case of skin contact (irritant).

Special Remarks on Toxicity to Animals: Not available.

Special Remarks on Chronic Effects on Humans: Not available.

Special Remarks on other Toxic Effects on Humans: Material is irritating to mucous membranes and upper respiratory

tract.

 

Section 12: Ecological Information

Ecotoxicity: Not available.

BOD5 and COD: Not available.

Products of Biodegradation:

Possibly hazardous short term degradation products are not likely. However, long term degradation products may

arise.

Toxicity of the Products of Biodegradation: The products of degradation are as toxic as the original product.

Special Remarks on the Products of Biodegradation: Not available.

 

Section 13: Disposal Considerations

Waste Disposal:

 

Section 14: Transport Information

DOT Classification: CLASS 6.1: Poisonous material.

Identification: : Toluidine : UN1708 PG: II

Special Provisions for Transport: Not available.

 

Section 15: Other Regulatory Information

Federal and State Regulations:

California prop. 65: This product contains the following ingredients for which the State of California has found to

cause cancer, birth defects or other reproductive harm, which would require a warning under the statute:

o-Toluidine AR

California prop. 65: This product contains the following ingredients for which the State of California has found to

cause cancer which would require a warning under the statute: ortho-Toluidine

Pennsylvania RTK: ortho-Toluidine

Massachusetts RTK: ortho-Toluidine

TSCA 8(b) inventory: ortho-Toluidine

SARA 313 toxic chemical notification and release reporting: ortho-Toluidine

CERCLA: Hazardous substances.: ortho-Toluidine

Other Regulations: OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200).

Other Classifications:

WHMIS (Canada):

CLASS B-3: Combustible liquid with a flash point between 37.8°C (100°F) and 93.3°C

(200°F).

CLASS D-1A: Material causing immediate and serious toxic effects (VERY TOXIC).

CLASS D-2A: Material causing other toxic effects (VERY TOXIC).

DSCL (EEC):

R36/38- Irritating to eyes and skin.

R45- May cause cancer.

R46- May cause heritable genetic

damage.

HMIS (U.S.A.):

Health Hazard: 3

Fire Hazard: 2

Reactivity: 0

Personal Protection: h

National Fire Protection Association (U.S.A.):

Health: 3

Flammability: 2

Reactivity: 0

Specific hazard:

Protective Equipment:

Gloves.

Lab coat.

Vapor respirator. Be sure to use an

approved/certified respirator or

equivalent. Wear appropriate respirator

when ventilation is inadequate.

Splash goggles.

 

Section 16: Other Information

References:

-Guide de la loi et du règlement sur le transport des marchandises dangeureuses au canada. Centre de conformité

internatinal Ltée. 1986.

-Hawley, G.G.. The Condensed Chemical Dictionary, 11e ed., New York N.Y., Van Nostrand Reinold, 1987.

-Material safety data sheet emitted by: la Commission de la Santé et de la Sécurité du Travail du Québec.

-SAX, N.I. Dangerous Properties of Indutrial Materials. Toronto, Van Nostrand Reinold, 6e ed. 1984.

-The Sigma-Aldrich Library of Chemical Safety Data, Edition II.

Other Special Considerations: Not available.

Created: 10/10/2005 12:06 AM

Last Updated: 11/06/2008 12:00 PM