Papain Purified MSDS

Section 1: Chemical Product and Company Identification

Product Name: Papain Purified

Catalog Codes: SLP1258

CAS#: 9001-73-4

RTECS: RU4950000

TSCA: TSCA 8(b) inventory: Papain Purified

CI#: Not available.

Synonym: Arbuz, Caroid, Nematolyt, Papayotin,

Summetrin, Tromasin, Vegetable pepsin, Velardon,

Vermizym; Papain, 100 milk clotting units/g

Chemical Name: Papain

Chemical Formula: Not available.

Section 2: Composition and Information on Ingredients

Composition:

Name CAS # % by Weight

Papain Purified 9001-73-4 100

Toxicological Data on Ingredients: Papain : ORAL (LD50): Acute: 4000 mg/kg [Rat]. 12500 mg/kg [Mouse].

Section 3: Hazards Identification

Potential Acute Health Effects:

Hazardous in case of eye contact (irritant), of inhalation. Slightly hazardous in case of skin contact (irritant), of

ingestion.

Potential Chronic Health Effects:

CARCINOGENIC EFFECTS: Not available.

MUTAGENIC EFFECTS: Not available.

TERATOGENIC EFFECTS: Not available.

DEVELOPMENTAL TOXICITY: Not available.

Repeated or prolonged exposure is not known to aggravate medical condition.

Section 4: First Aid Measures

Eye Contact:

Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at

least 15 minutes. Cold water may be used. Get medical attention.

Skin Contact:

Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.

Cold water may be used.

Serious Skin Contact: Not available.

Inhalation:

If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get

medical attention.

Serious Inhalation: Not available.

Ingestion:

Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an

unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight

clothing such as a collar, tie, belt or waistband.

Serious Ingestion: Not available.

Section 5: Fire and Explosion Data

Flammability of the Product: May be combustible at high temperature.

Auto-Ignition Temperature: Not available.

Flash Points: Not available.

Flammable Limits: Not available.

Products of Combustion: Not available.

Fire Hazards in Presence of Various Substances: Slightly flammable to flammable in presence of open flames and sparks,

of heat.

Explosion Hazards in Presence of Various Substances:

Risks of explosion of the product in presence of mechanical impact: Not available.

Risks of explosion of the product in presence of static discharge: Not available.

Fire Fighting Media and Instructions:

SMALL FIRE: Use DRY chemical powder.

LARGE FIRE: Use water spray, fog or foam. Do not use water jet.

Special Remarks on Fire Hazards: Not available.

Special Remarks on Explosion Hazards: Not available.

Section 6: Accidental Release Measures

Small Spill:

Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by

spreading water on the contaminated surface and dispose of according to local and regional authority

requirements.

Large Spill:

Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water

on the contaminated surface and allow to evacuate through the sanitary system.

Section 7: Handling and Storage

Precautions:

Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not

breathe dust. Avoid contact with eyes. Wear suitable protective clothing. In case of insufficient ventilation, wear

suitable respiratory equipment. If you feel unwell, seek medical attention and show the label when possible.

Storage:

Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 8°C (46.4°F).

Refrigerate

Section 8: Exposure Controls/Personal Protection

Engineering Controls:

Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below

recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to

airborne contaminants below the exposure limit.

Personal Protection:

Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent.

Gloves.

Personal Protection in Case of a Large Spill:

Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used

to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist

BEFORE handling this product.

Exposure Limits: Not available.

Section 9: Physical and Chemical Properties

Physical state and appearance: Solid. (Powdered solid.)

Odor: Not available.

Taste: Not available.

Molecular Weight: Not available.

Color: Grayish white.

pH (1% soln/water): Not available.

Boiling Point: Not available.

Melting Point: Not available.

Critical Temperature: Not available.

Specific Gravity: Not available.

Vapor Pressure: Not applicable.

Vapor Density: Not available.

Volatility: Not available.

Odor Threshold: Not available.

Water/Oil Dist. Coeff.: Not available.

Ionicity (in Water): Not available.

Dispersion Properties: See solubility in water.

Solubility: Soluble in cold water.

Section 10: Stability and Reactivity Data

Stability: The product is stable.

Instability Temperature: Not available.

Conditions of Instability: Excess heat, dust generation, incompatible materials

Incompatibility with various substances: Not available.

Corrosivity: Non-corrosive in presence of glass.

Special Remarks on Reactivity: Sensitive to light.

Special Remarks on Corrosivity: Not available.

Polymerization: Will not occur.

Section 11: Toxicological Information

Routes of Entry: Inhalation. Ingestion.

Toxicity to Animals: Acute oral toxicity (LD50): 4000 mg/kg [Rat].

Chronic Effects on Humans: Not available.

Other Toxic Effects on Humans:

Hazardous in case of skin contact (irritant), of inhalation (lung irritant, lung sensitizer).

Slightly hazardous in case of ingestion, .

Special Remarks on Toxicity to Animals: Not available.

Special Remarks on Chronic Effects on Humans:

May cause adverse reproductive effects and birth defects (teratogenic) based on animal test data. No human

data found.

Special Remarks on other Toxic Effects on Humans:

Acute Potential Health Effects:

Skin: Causes skin irritation.

Eyes: Causes eye irritation. Symptoms may include coughing, wheezing, and/orshortness of breath (dyspnea)

Inhalation: Causes respiratory tract and mucous membrane irritation. Symptoms may include coughing,

wheezing. Exposure to airborne papain may also elicit type I hypersensitivity reactions and asthmatic symptoms.

Ingestion: May cause stomach upset, hypermotility and diarrhea.

Chronic Potential Health Effects:

Inhalation: Prolonged or repeated inhalation may cause emphysema.

Section 12: Ecological Information

Ecotoxicity: Not available.

BOD5 and COD: Not available.

Products of Biodegradation:

Possibly hazardous short term degradation products are not likely. However, long term degradation products may

arise.

Toxicity of the Products of Biodegradation: Not available.

Special Remarks on the Products of Biodegradation: Not available.

Section 13: Disposal Considerations

Waste Disposal:

Waste must be disposed of in accordance with federal, state and local environmental

control regulations.

Section 14: Transport Information

DOT Classification: Not a DOT controlled material (United States).

Identification: Not applicable.

Special Provisions for Transport: Not applicable.

Section 15: Other Regulatory Information

Federal and State Regulations: TSCA 8(b) inventory: Papain

Other Regulations: Not available.

Other Classifications:

WHMIS (Canada): Not controlled under WHMIS (Canada).

DSCL (EEC):

R36/37/38- Irritating to eyes,

respiratory system and skin.

R42- May cause sensitization by

inhalation.

S22- Do not breathe dust.

S24- Avoid contact with skin.

S26- In case of contact with eyes, rinse

immediately with plenty of water and seek

medical advice.

S36/37- Wear suitable protective clothing and

gloves.

HMIS (U.S.A.):

Health Hazard: 2

Fire Hazard: 1

Reactivity: 0

Personal Protection: E

National Fire Protection Association (U.S.A.):

Health: 2

Flammability: 1

Reactivity: 0

Specific hazard:

Protective Equipment:

Gloves.

Lab coat.

Dust respirator. Be sure to use an

approved/certified respirator or

equivalent.

Splash goggles.

Section 16: Other Information

References: Not available.

Other Special Considerations: Not available.

Created: 10/10/2005 11:10 AM

Last Updated: 11/06/2008 12:00 PM