MSDS Number: P3148 * * * * * Effective Date: 07/20/07 * * * * * Supercedes: 05/07/07 PHENYLHYDRAZINE


PHENYLHYDRAZINE


1. Product Identification

Synonyms: Hydrazinobenzene
CAS No.: 100-63-0
Molecular Weight: 108.15
Chemical Formula: C6H5NHNH2
Product Codes: 1921

2. Composition/Information on Ingredients


 
  Ingredient                                CAS No         Percent        Hazardous                                  
  ---------------------------------------   ------------   ------------   ---------   
 
  Phenylhydrazine                           100-63-0         90 - 100%       Yes                                                                    
 

3. Hazards Identification

Emergency Overview
--------------------------
DANGER! HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. CORROSIVE. CAUSES BURNS TO ANY AREA OF CONTACT. AFFECTS BLOOD, LIVER, KIDNEYS AND RESPIRATORY SYSTEM. MAY CAUSE ALLERGIC SKIN REACTION. CAUSES IRRITATION TO RESPIRATORY TRACT. COMBUSTIBLE SOLID, LIQUID AND VAPOR.

SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 3 - Severe (Poison)
Flammability Rating: 2 - Moderate
Reactivity Rating: 1 - Slight
Contact Rating: 3 - Severe (Life)
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER GLOVES; CLASS B EXTINGUISHER
Storage Color Code: Red (Flammable)
-----------------------------------------------------------------------------------------------------------

Potential Health Effects
----------------------------------

All routes of exposure can produce hemolytic anemia (breakdown of the red blood cells) with resultant injury to liver and kidneys.

Inhalation:
Poison. Corrosive to the respiratory tract. May produce sore throat, coughing, labored breathing, dizziness, bluish skin, faintness.
Ingestion:
Toxic.Corrosive to tissues. May cause vomiting, dizziness, faintness, and jaundice.
Skin Contact:
Corrosive. Contact dermatitis and skin sensitization may occur. Other symptoms include redness, pain, burns; skin absorption can happen readily and produce toxic effects noted for inhalation and ingestion.
Eye Contact:
Corrosive. Vapors and liquid are destructive to eye tissue.
Chronic Exposure:
Chronic and acute exposures may produce blood effects, liver and kidney damage. Suspect cancer hazard.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders or eye problems, or impaired liver, kidney or respiratory function may be more susceptible to the effects of the substance.

4. First Aid Measures

Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention immediately.
Ingestion:
If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never give anything by mouth to an unconscious person. Get medical attention immediately.
Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention immediately. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.

5. Fire Fighting Measures

Fire:
Flash point: 88C (190F) CC
Combustible. Contact with strong oxidizers may cause fire.
Explosion:
Above the flash point, explosive vapor-air mixtures may be formed.
Fire Extinguishing Media:
Alcohol foam.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.

6. Accidental Release Measures

Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from entering. Contain and recover liquid when possible. Use non-sparking tools and equipment. Collect liquid in an appropriate container or absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Do not use combustible materials, such as saw dust. Do not flush to sewer!

7. Handling and Storage

Keep in a tightly closed container. Store in a cool, dry, ventilated area away from sources of heat or ignition. Protect against physical damage. Store separately from reactive or combustible materials, and out of direct sunlight. Product may solidify at room temperature. Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed for the product.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
-OSHA Permissible Exposure Limit (PEL):
5 ppm (TWA), skin
-ACGIH Threshold Limit Value (TLV):
0.1 ppm (TWA) skin, category A3-animal carcinogen.
-NIOSH recommended exposure limit (REL):
0.6 mg/m3/2H, ceiling concentration, skin
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded and engineering controls are not feasible, wear a supplied air, full-facepiece respirator, airlined hood, or full-facepiece self-contained breathing apparatus. Breathing air quality must meet the requirements of the OSHA respiratory protection standard (29CFR1910.134).
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact. Vinyl-coated, rubber or neoprene materials are suitable for personal protective equipment.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.

9. Physical and Chemical Properties

Appearance:
Colorless liquid, becomes red-brown on exposure to air.
Odor:
Faint aromatic odor.
Solubility:
Slightly soluble in hot water.
Specific Gravity:
1.10 @ 20C/4C
pH:
No information found.
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
243.5C (471F)
Melting Point:
19C (66F)
Vapor Density (Air=1):
3.7
Vapor Pressure (mm Hg):
1 @ 71.8C (162F)
Evaporation Rate (BuAc=1):
No information found.

10. Stability and Reactivity

Stability:
Stable under ordinary conditions of use and storage. Turns yellow to dark red on exposure to air and light; forms a hemihydrate.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizers, lead dioxide.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.

11. Toxicological Information

Toxicological Data:
Oral rat LD50: 188 mg/kg; inhalation rat LC50: 2610 mg/m3. Investigated as a tumorigen, mutagen, reproductive effector.
Reproductive Toxicity:
In laboratory animals, this compound has caused both birth defects and damage to the reproductive system.
 
  --------\Cancer Lists\------------------------------------------------------
                                         ---NTP Carcinogen---
  Ingredient                             Known    Anticipated    IARC Category
  ------------------------------------   -----    -----------    -------------
  Phenylhydrazine (100-63-0)              No          No            None

12. Ecological Information

Environmental Fate:
When released into the soil, this material is expected to leach into groundwater. When released into the soil, this material is not expected to evaporate significantly. When released into water, this material is not expected to evaporate significantly. This material has an estimated bioconcentration factor (BCF) of less than 100. This material is not expected to significantly bioaccumulate. When released into the air, this material may be moderately degraded by reaction with photochemically produced hydroxyl radicals. When released into the air, this material may be moderately degraded by photolysis. When released into the air, this material is expected to have a half-life of less than 1 day.
Environmental Toxicity:
No information found.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste facility. Although not a listed RCRA hazardous waste, this material may exhibit one or more characteristics of a hazardous waste and require appropriate analysis to determine specific disposal requirements. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.

14. Transport Information

Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: PHENYLHYDRAZINE
Hazard Class: 6.1
UN/NA: UN2572
Packing Group: II
Information reported for product/size: 500G

International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: PHENYLHYDRAZINE
Hazard Class: 6.1
UN/NA: UN2572
Packing Group: II
Information reported for product/size: 500G


15. Regulatory Information

 
  --------\Chemical Inventory Status - Part 1\---------------------------------
  Ingredient                                       TSCA  EC   Japan  Australia
  -----------------------------------------------  ----  ---  -----  ---------
  Phenylhydrazine (100-63-0)                        Yes  Yes   Yes      Yes                                      
 
  --------\Chemical Inventory Status - Part 2\---------------------------------
                                                          --Canada--
  Ingredient                                       Korea  DSL   NDSL  Phil.
  -----------------------------------------------  -----  ---   ----  -----
  Phenylhydrazine (100-63-0)                        Yes   Yes   No     Yes       
 
  --------\Federal, State & International Regulations - Part 1\----------------
                                             -SARA 302-    ------SARA 313------
  Ingredient                                 RQ    TPQ     List  Chemical Catg.
  -----------------------------------------  ---   -----   ----  --------------
  Phenylhydrazine (100-63-0)                 No    No      No         No
 
  --------\Federal, State & International Regulations - Part 2\----------------
                                                        -RCRA-    -TSCA-
  Ingredient                                 CERCLA     261.33     8(d) 
  -----------------------------------------  ------     ------    ------
  Phenylhydrazine (100-63-0)                 No         No         Yes    
 
 
Chemical Weapons Convention:  No     TSCA 12(b):  No     CDTA:  No
SARA 311/312:  Acute: Yes      Chronic: Yes  Fire: Yes Pressure: No
Reactivity: No          (Pure / Liquid)
WARNING:
THIS PRODUCT CONTAINS A CHEMICAL(S) KNOWN TO THE STATE OF CALIFORNIA TO CAUSE CANCER.

Australian Hazchem Code: 3X
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.

16. Other Information

NFPA Ratings: Health: 3 Flammability: 2 Reactivity: 0
Label Hazard Warning:
DANGER! HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. CORROSIVE. CAUSES BURNS TO ANY AREA OF CONTACT. AFFECTS BLOOD, LIVER, KIDNEYS AND RESPIRATORY SYSTEM. MAY CAUSE ALLERGIC SKIN REACTION. CAUSES IRRITATION TO RESPIRATORY TRACT. COMBUSTIBLE SOLID, LIQUID AND VAPOR.
Label Precautions:
Do not breathe vapor.
Do not get in eyes, on skin, or on clothing.
Keep container closed.
Use only with adequate ventilation.
Wash thoroughly after handling.
Keep away from heat and flame.
Label First Aid:
In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never give anything by mouth to an unconscious person. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. In all cases get medical attention immediately.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(s) changed since last revision of document include: 3.
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Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)