Synonyms: 4-Methylbenzenesulfonic acid; Tosic acid; p-TSA; p-Tolylsulfonic acid
CAS No.: 104-15-4 (Anhydrous) 6192-52-5 (Monohydrate)
Molecular Weight: 190.22
Chemical Formula: C7H8O3S.H2O
Product Codes:
J.T. Baker: W031, W034
Mallinckrodt: 1938
Ingredient CAS No Percent Hazardous --------------------------------------- ------------ ------------ --------- Toluene Sulfonic Acid 104-15-4 99 - 100% Yes
Emergency Overview
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DANGER! CORROSIVE. CAUSES BURNS. HARMFUL IF SWALLOWED OR INHALED. MATERIAL IS EXTREMELY DESTRUCTIVE TO THE UPPER RESPIRATORY TRACT, EYES AND SKIN.
SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 3 - Severe
Flammability Rating: 1 - Slight
Reactivity Rating: 2 - Moderate
Contact Rating: 3 - Severe (Corrosive)
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER GLOVES
Storage Color Code: White (Corrosive)
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Potential Health Effects
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Information on the human health effects from exposure to this substance is limited.
Inhalation:
Corrosive. Extremely destructive to tissues of the mucous membranes and upper respiratory tract. Symptoms may include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea and vomiting. Inhalation may be fatal as a result of spasm inflammation and edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema.
Ingestion:
Extremely destructive to tissues. May be fatal.
Skin Contact:
Extremely destructive to skin. Causes irritation, redness, pain, and burns.
Eye Contact:
Extremely destructive to eyes. Causes irritation, redness, pain, and burns.
Chronic Exposure:
No information found.
Aggravation of Pre-existing Conditions:
No information found.
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician immediately.
Ingestion:
DO NOT INDUCE VOMITING. Give large quantities of water. Never give anything by mouth to an unconscious person. Call a physician immediately.
Skin Contact:
In case of contact, wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. Call a physician immediately.
Eye Contact:
Immediately flush eyes with gentle but large stream of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Call a physician immediately.
Fire:
Flash point: 184C (363F) CC
Autoignition temperature: 350C (662F)
As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source.
Explosion:
Not considered to be an explosion hazard.
Fire Extinguishing Media:
Water spray, dry chemical, alcohol foam, or carbon dioxide. May react strongly with water.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
Remove all sources of ignition. Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Keep unnecessary and unprotected personnel from entering hazard area.
Spills: Clean up spills in a manner that does not disperse dust into the air. Use non-sparking tools and equipment. Reduce airborne dust and prevent scattering by moistening with water. Pick up spill for recovery or disposal and place in a closed container.
Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Isolate from incompatible substances. Protect from moisture. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.
Airborne Exposure Limits:
None established.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn. If oil particles (e.g. lubricants, cutting fluids, glycerine, etc.) are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Appearance:
Off-white crystals.
Odor:
Odorless when pure; technical grade has a slight aromatic odor
Solubility:
67g/100mL water, anhydrous.
Density:
1.23-1.24 g/cm3 at 20C (anhydrous)
pH:
No information found.
% Volatiles by volume @ 21C (70F):
No information found.
Boiling Point:
140C (284F) @ 20mm , anhydrous
Melting Point:
103 - 106C (217 - 223F)
Vapor Density (Air=1):
6.0
Vapor Pressure (mm Hg):
No information found.
Evaporation Rate (BuAc=1):
No information found.
Stability:
Stable under ordinary conditions of use and storage. A strong acid when dissolved when dissolved in water, the solution is corrosive and reacts violently with bases.
Hazardous Decomposition Products:
Burning may produce carbon monoxide, carbon dioxide, sulfur oxides.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Solution is a strong acid. Incompatible with sulfuric acid, caustics, ammonia, amines, amides, organic anhydrides, isocyanates, vinyl acetate, alkylene oxide and epichlorohydrin. Attacks metals in the presence of moisture and produces hydrogen gas.
Conditions to Avoid:
No information found.
For anhydrous p-Toluenesulfonic acid: Oral rat LD50: 2480 mg/kg.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Toluene Sulfonic Acid (104-15-4) No No None
Environmental Fate:
When released into the soil, this material is expected to leach into groundwater. When released into water, this material may biodegrade to a moderate extent. When released into water, this material is not expected to evaporate significantly. When released into the air, this material is expected to be readily removed from the atmosphere by wet deposition. This material is not expected to significantly bioaccumulate.
Environmental Toxicity:
No information found.
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste facility. Although not a listed RCRA hazardous waste, this material may exhibit one or more characteristics of a hazardous waste and require appropriate analysis to determine specific disposal requirements. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: ALKYL SULFONIC ACID, SOLID (WITH NOT MORE THAN 5% FREE SULFURIC ACID)
Hazard Class: 8
UN/NA: UN2585
Packing Group: III
Information reported for product/size: 500G
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: ALKYLSULPHONIC ACID, SOLID (WITH NOT MORE THAN 5% FREE SULPHURIC ACID)
Hazard Class: 8
UN/NA: UN2585
Packing Group: III
Information reported for product/size: 500G
International (Air, I.C.A.O.)
-----------------------------
Proper Shipping Name: ALKYLSULPHONIC ACID, SOLID (WITH NOT MORE THAN 5% FREE SULPHURIC ACID)
Hazard Class: 8
UN/NA: UN2585
Packing Group: III
Information reported for product/size: 500G
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Toluene Sulfonic Acid (104-15-4) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Toluene Sulfonic Acid (104-15-4) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Toluene Sulfonic Acid (104-15-4) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Toluene Sulfonic Acid (104-15-4) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: No Fire: No Pressure: No
Reactivity: No (Pure / Solid)
Australian Hazchem Code: 2X
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.
NFPA Ratings: Health: 3 Flammability: 1 Reactivity: 0
Label Hazard Warning:
DANGER! CORROSIVE. CAUSES BURNS. HARMFUL IF SWALLOWED OR INHALED. MATERIAL IS EXTREMELY DESTRUCTIVE TO THE UPPER RESPIRATORY TRACT, EYES AND SKIN.
Label Precautions:
Do not breathe dust.
Do not get in eyes, on skin, or on clothing.
Keep container closed.
Use only with adequate ventilation.
Wash thoroughly after handling.
Label First Aid:
In all cases call a physician immediately. In case of contact, wipe off excess material from skin then immediately flush eyes or skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never give anything by mouth to an unconscious person.
Product Use:
Laboratory Reagent.
Revision Information:
No Changes.
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Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)