Synonyms: Schiff's Reagent; Fuchsin-sulfite reagent
CAS No.: Not applicable to mixtures.
Molecular Weight: Not applicable to mixtures.
Chemical Formula: Not applicable to mixtures.
Product Codes:
J.T. Baker: U973
Mallinckrodt: E070, H278
Ingredient CAS No Percent Hazardous --------------------------------------- ------------ ------------ --------- Pararosaniline 569-61-9 < 0.5% Yes Sodium Bisulfite 7631-90-5 < 1% No Hydrogen Chloride 7647-01-0 < 1% Yes Water 7732-18-5 > 97% No
Emergency Overview
--------------------------
CAUTION! MAY CAUSE IRRITATION TO SKIN, EYES, AND RESPIRATORY TRACT. POSSIBLE CANCER HAZARD. CONTAINS PARAROSANILINE WHICH MAY CAUSE CANCER BASED ON ANIMAL DATA. Risk of cancer depends upon duration and level of exposure.
SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 3 - Severe (Cancer Causing)
Flammability Rating: 0 - None
Reactivity Rating: 1 - Slight
Contact Rating: 4 - Extreme (Corrosive)
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER GLOVES
Storage Color Code: White (Corrosive)
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Potential Health Effects
----------------------------------
Inhalation:
May cause irritation to the respiratory tract. Symptoms may include coughing and shortness of breath. May cause allergic reaction in sensitive individuals.
Ingestion:
May cause irritation to the gastrointestinal tract. Symptoms may include nausea, vomiting and diarrhea.
Skin Contact:
May cause irritation with redness and pain. Prolonged contact may cause dermatitis.
Eye Contact:
May cause irritation, redness and pain.
Chronic Exposure:
Compound has been shown to cause cancer in animals and may be linked to cancer in humans. Has shown mutagenic effects in laboratory studies.
Aggravation of Pre-existing Conditions:
Some individuals are said to be dangerously sensitive to minute amounts of sulfites in foods. Symptoms may include broncho constriction, shock, gastrointestinal disturbances, angio edema, flushing, and tingling sensations. Once allergy develops, future exposures can cause asthma attacks with shortness of breath, wheezing, and cough.
Inhalation:
Remove to fresh air. Get medical attention for any breathing difficulty.
Ingestion:
If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never give anything by mouth to an unconscious person. Get medical attention immediately.
Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention if irritation develops.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids occasionally. Get medical attention if irritation persists.
Fire:
Not expected to be a fire hazard.
Explosion:
Contact of concentrated solutions with most metals causes formation of flammable and explosive hydrogen gas.
Fire Extinguishing Media:
Use extinguishing media appropriate for surrounding fire.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from entering. Contain and recover liquid when possible. Neutralize with alkaline material (soda ash, lime), then absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Do not use combustible materials, such as saw dust. Do not flush to sewer!
Store at controlled room temperature 15-30C (59-86F). Keep in a tightly closed container, stored in a dry, well ventilated area. Protect against physical damage. Protect from freezing. Wear special protective equipment (Sec. 8) for maintenance break-in or where exposures may exceed established exposure levels. Wash hands, face, forearms and neck when exiting restricted areas. Shower, dispose of outer clothing, change to clean garments at the end of the day. Avoid cross-contamination of street clothes. Wash hands before eating and do not eat, drink, or smoke in workplace. Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed for the product.
Airborne Exposure Limits:
For Hydrochloric acid:
- OSHA Permissible Exposure Limit (PEL):
5 ppm (Ceiling)
- ACGIH Threshold Limit Value (TLV):
2 ppm (Ceiling), A4 Not classifiable as a human carcinogen
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded and engineering controls are not feasible, a full facepiece respirator with an acid gas cartridge may be worn up to 50 times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection:
Rubber or neoprene gloves and additional protection including impervious boots, apron, or coveralls, as needed in areas of unusual exposure to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Appearance:
Clear, colorless liquid.
Odor:
Pungent odor of sulfur dioxide.
Solubility:
Complete (100%)
Specific Gravity:
1.00
pH:
1.1 - 1.5
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
ca. 100C (ca. 212F)
Melting Point:
ca. 0C (ca. 32F)
Vapor Density (Air=1):
Not applicable.
Vapor Pressure (mm Hg):
Essentially the same as water.
Evaporation Rate (BuAc=1):
Essentially the same as water.
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Hydrogen chloride, oxides of sulfur, carbon monoxide, carbon dioxide.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong bases, metals, metal oxides, hydroxides, amines, carbonates and other alkaline materials, cyanides, sulfides,sulfites, and formaldehyde.
Conditions to Avoid:
Incompatibles.
Hydrochloric acid: Inhalation rat LC50: 3124 ppm/1H; oral rabbit LD50: 900 mg/kg. Investigated as a tumorigen, mutagen, reproductive effector. Sodium bisulfite [7631-90-5]: oral rat LD50: 2 gram/kg. Investigated as a tumorigen and mutagen. Pararosanilinehydrochloride: No LD50/LC50 information found relating to normal routes of occupational exposure. Investigated as a tumorigen and mutagen.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Pararosaniline (569-61-9) No Yes 2B
Sodium Bisulfite (7631-90-5) No No 3
Hydrogen Chloride (7647-01-0) No No 3
Water (7732-18-5) No No None
Environmental Fate:
No information found.
Environmental Toxicity:
No information found.
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, INORGANIC, N.O.S. (HYDROCHLORIC ACID, SODIUM BISULFITE)
Hazard Class: 8
UN/NA: UN3264
Packing Group: III
Information reported for product/size: 500ML
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, INORGANIC, N.O.S. (HYDROCHLORIC ACID, SODIUM BISULFITE)
Hazard Class: 8
UN/NA: UN3264
Packing Group: III
Information reported for product/size: 500ML
International (Air, I.C.A.O.)
-----------------------------
Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, INORGANIC, N.O.S. (HYDROCHLORIC ACID, SODIUM BISULFITE)
Hazard Class: 8
UN/NA: UN3264
Packing Group: III
Information reported for product/size: 500ML
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Pararosaniline (569-61-9) Yes Yes No No
Sodium Bisulfite (7631-90-5) Yes Yes Yes Yes
Hydrogen Chloride (7647-01-0) Yes Yes Yes Yes
Water (7732-18-5) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Pararosaniline (569-61-9) No Yes No Yes
Sodium Bisulfite (7631-90-5) Yes Yes No Yes
Hydrogen Chloride (7647-01-0) Yes Yes No Yes
Water (7732-18-5) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Pararosaniline (569-61-9) No No No No
Sodium Bisulfite (7631-90-5) No No No No
Hydrogen Chloride (7647-01-0) 5000 500* Yes No
Water (7732-18-5) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Pararosaniline (569-61-9) No No No
Sodium Bisulfite (7631-90-5) 5000 No Yes
Hydrogen Chloride (7647-01-0) 5000 No No
Water (7732-18-5) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: No Pressure: No
Reactivity: No (Mixture / Liquid)
WARNING:
THIS PRODUCT CONTAINS A CHEMICAL(S) KNOWN TO THE STATE OF CALIFORNIA TO CAUSE CANCER.
Australian Hazchem Code: None allocated.
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.
NFPA Ratings: Health: 2 Flammability: 0 Reactivity: 0
Label Hazard Warning:
CAUTION! MAY CAUSE IRRITATION TO SKIN, EYES, AND RESPIRATORY TRACT. POSSIBLE CANCER HAZARD. CONTAINS PARAROSANILINE WHICH MAY CAUSE CANCER BASED ON ANIMAL DATA. Risk of cancer depends upon duration and level of exposure.
Label Precautions:
Do not get in eyes, on skin, or on clothing.
Wash thoroughly after handling.
Do not breathe vapor.
Keep container closed.
Use with adequate ventilation.
Label First Aid:
If inhaled, remove to fresh air. Get medical attention for any breathing difficulty. In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(s) changed since last revision of document include: 14.
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Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)