MSDS Number: T0689 * * * * * Effective Date: 11/21/08 * * * * * Supercedes: 02/16/06 Tetrabutylammonium Hydroxide, 25% in Methanol


Tetrabutylammonium Hydroxide, 25% in Methanol


1. Product Identification

Synonyms: None
CAS No.: Not applicable to mixtures.
Molecular Weight: Not applicable to mixtures.
Chemical Formula: Not applicable to mixtures.
Product Codes: V362

2. Composition/Information on Ingredients


 
  Ingredient                                CAS No         Percent        Hazardous                                  
  ---------------------------------------   ------------   ------------   ---------   
 
  Tetrabutylammonium Hydroxide              2052-49-5        24 - 26%        Yes                                                                   
  Methyl Alcohol                            67-56-1          74 - 76%        Yes                                                                   
 

3. Hazards Identification

Emergency Overview
--------------------------
POISON! DANGER! CORROSIVE. CAUSES BURNS TO SKIN AND EYES. VAPOR HARMFUL. MAY BE FATAL OR CAUSE BLINDNESS IF SWALLOWED. HARMFUL IF INHALED OR ABSORBED THROUGH SKIN. CANNOT BE MADE NONPOISONOUS. FLAMMABLE LIQUID AND VAPOR. AFFECTS THE CENTRAL NERVOUS SYSTEM, GASTROINTESTINAL TRACT AND LIVER.

SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 3 - Severe (Poison)
Flammability Rating: 3 - Severe (Flammable)
Reactivity Rating: 1 - Slight
Contact Rating: 3 - Severe (Corrosive)
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER GLOVES; CLASS B EXTINGUISHER
Storage Color Code: Red (Flammable)
-----------------------------------------------------------------------------------------------------------

Potential Health Effects
----------------------------------

Inhalation:
Methanol: A slight irritant to the mucous membranes. Toxic effects exerted upon nervous system, particularly the optic nerve. Once absorbed into the body, it is very slowly eliminated. Symptoms of overexposure may include headache, drowsiness, nausea, vomiting, blurred vision, blindness, coma, and death. A person may get better but then worse again up to 30 hours later.
Tetrabutylammonium hydroxide: No information found, but compound should be handled as a potential health hazard.
Ingestion:
Methanol: Toxic. Symptoms parallel inhalation. Can intoxicate and cause blindness. Usual fatal dose: 100-125 milliliters.
Tetrabutylammonium hydroxide: No information found, but compound should be handled as a potential health hazard.
Skin Contact:
Tetrabutylammonium hydroxide: Corrosive. Symptoms of redness, pain, and severe burn can occur. May be absorbed through the skin with possible systemic effects. Methyl alcohol is a defatting agent and may cause skin to become dry and cracked. Skin absorption can occur; symptoms may parallel inhalation exposure.
Eye Contact:
Tetrabutylammonium hydroxide: Corrosive. Contact can cause blurred vision, redness, pain and severe tissue burns. Methanol is an eye irritant. Continued exposure may cause eye lesions.
Chronic Exposure:
Methanol: Marked impairment of vision has been reported. Repeated or prolonged exposure may cause skin irritation.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders or eye problems or impaired liver or kidney function may be more susceptible to the effects of the substance.

4. First Aid Measures

Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention immediately.
Ingestion:
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention immediately.
Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention immediately. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.

5. Fire Fighting Measures

Fire:
Flash point: 11C (52F) CC
Autoignition temperature: 464C (867F)
Flammable limits in air % by volume:
lel: 6.0; uel: 36.0
Listed fire data is for Methanol. Flammable Liquid and Vapor!
Explosion:
Moderate explosion hazard and dangerous fire hazard when exposed to heat, sparks or flames. Vapors can flow along surfaces to distant ignition source and flash back. Above flash point, vapor-air mixtures are explosive within flammable limits noted above. Sealed containers may rupture when heated. Sensitive to static discharge.
Fire Extinguishing Media:
Water spray, dry chemical, alcohol foam, or carbon dioxide.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode. Use water spray to blanket fire, cool fire exposed containers, and to flush non-ignited spills or vapors away from fire.

6. Accidental Release Measures

Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from entering. Contain and recover liquid when possible. Use non-sparking tools and equipment. Collect liquid in an appropriate container or absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Do not use combustible materials, such as saw dust. Do not flush to sewer! If a leak or spill has not ignited, use water spray to disperse the vapors, to protect personnel attempting to stop leak, and to flush spills away from exposures. US Regulations (CERCLA) require reporting spills and releases to soil, water and air in excess of reportable quantities. The toll free number for the US Coast Guard National Response Center is (800) 424-8802.


J. T. Baker SOLUSORB® solvent adsorbent is recommended for spills of this product.

7. Handling and Storage

Protect against physical damage. Store in a cool, dry well-ventilated location, away from any area where the fire hazard may be acute. Outside or detached storage is preferred. Separate from incompatibles. Containers should be bonded and grounded for transfers to avoid static sparks. Storage and use areas should be No Smoking areas. Use non-sparking type tools and equipment, including explosion proof ventilation. Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed for the product. Do Not attempt to clean empty containers since residue is difficult to remove. Do not pressurize, cut, weld, braze, solder, drill, grind or expose such containers to heat, sparks, flame, static electricity or other sources of ignition: they may explode and cause injury or death.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
For Methyl Alcohol:
- OSHA Permissible Exposure Limit (PEL):
200 ppm (TWA)
- ACGIH Threshold Limit Value (TLV):
200 ppm (TWA), 250 ppm (STEL) skin
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded, wear a supplied air, full-facepiece respirator, airlined hood, or full-facepiece self-contained breathing apparatus.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.

9. Physical and Chemical Properties

Appearance:
Clear, colorless liquid.
Odor:
No information found.
Solubility:
Complete (100%)
Specific Gravity:
0.83
pH:
No information found.
% Volatiles by volume @ 21C (70F):
75
Boiling Point:
65C (149F)
Melting Point:
No information found.
Vapor Density (Air=1):
Not applicable.
Vapor Pressure (mm Hg):
Not applicable.
Evaporation Rate (BuAc=1):
No information found.

10. Stability and Reactivity

Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Carbon oxides, nitrogen oxides and formaldehyde gas form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizing agents such as nitrates, perchlorates or sulfuric acid. Will attack some forms of plastics, rubber, and coatings. May react with metallic aluminum and generate hydrogen gas.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.

11. Toxicological Information


Methyl Alcohol (Methanol): LD50 oral rat 5628 mg/kg; LC50 inhalation rat 64000 ppm/4H; LD50 skin rabbit 15800 mg/kg; Irritation data-standard Draize test: skin, rabbit 20mg/24hr, moderate; eye, rabbit 100 mg/24 hr, moderate; Investigated as a mutagen and reproductive effector.
Tetrabutylammonium hydroxide: No LD50/LC50 information found relating to normal routes of occupational exposure.
 
  --------\Cancer Lists\------------------------------------------------------
                                         ---NTP Carcinogen---
  Ingredient                             Known    Anticipated    IARC Category
  ------------------------------------   -----    -----------    -------------
  Tetrabutylammonium Hydroxide            No          No            None
  (2052-49-5)
  Methyl Alcohol (67-56-1)                No          No            None

12. Ecological Information

Environmental Fate:
Methanol: When released into the soil, this material is expected to readily biodegrade. When released into the soil, this material is expected to leach into groundwater. When released into the soil, this material is expected to quickly evaporate. When released into the water, this material is expected to have a half-life between 1 and 10 days. When released into water, this material is expected to readily biodegrade. When released into the air, this material is expected to exist in the aerosol phase with a short half-life. When released into the air, this material is expected to be readily degraded by reaction with photochemically produced hydroxyl radicals. When released into air, this material is expected to have a half-life between 10 and 30 days. When released into the air, this material is expected to be readily removed from the atmosphere by wet deposition.
Environmental Toxicity:
Methanol: This material is expected to be slightly toxic to aquatic life.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be handled as hazardous waste and sent to a RCRA approved incinerator or disposed in a RCRA approved waste facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.

14. Transport Information

Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: FLAMMABLE LIQUID, CORROSIVE, N.O.S. (METHANOL, TETRABUTYLAMMONIUM HYDROXIDE)
Hazard Class: 3, 8
UN/NA: UN2924
Packing Group: II
Information reported for product/size: 100ML

International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: FLAMMABLE LIQUID, CORROSIVE, N.O.S. (METHANOL, TETRABUTYLAMMONIUM HYDROXIDE)
Hazard Class: 3, 8
UN/NA: UN2924
Packing Group: II
Information reported for product/size: 100ML

International (Air, I.C.A.O.)
-----------------------------
Proper Shipping Name: FLAMMABLE LIQUID, CORROSIVE, N.O.S. (METHANOL, TETRABUTYLAMMONIUM HYDROXIDE)
Hazard Class: 3, 8
UN/NA: UN2924
Packing Group: II
Information reported for product/size: 100ML

15. Regulatory Information

 
  --------\Chemical Inventory Status - Part 1\---------------------------------
  Ingredient                                       TSCA  EC   Japan  Australia
  -----------------------------------------------  ----  ---  -----  ---------
  Tetrabutylammonium Hydroxide (2052-49-5)          Yes  Yes   Yes      Yes                                      
  Methyl Alcohol (67-56-1)                          Yes  Yes   Yes      Yes                                      
 
  --------\Chemical Inventory Status - Part 2\---------------------------------
                                                          --Canada--
  Ingredient                                       Korea  DSL   NDSL  Phil.
  -----------------------------------------------  -----  ---   ----  -----
  Tetrabutylammonium Hydroxide (2052-49-5)          Yes   Yes   No     Yes                     
  Methyl Alcohol (67-56-1)                          Yes   Yes   No     Yes     
 
  --------\Federal, State & International Regulations - Part 1\----------------
                                             -SARA 302-    ------SARA 313------
  Ingredient                                 RQ    TPQ     List  Chemical Catg.
  -----------------------------------------  ---   -----   ----  --------------
  Tetrabutylammonium Hydroxide (2052-49-5)   No    No      No         No
  Methyl Alcohol (67-56-1)                   No    No      Yes        No
 
  --------\Federal, State & International Regulations - Part 2\----------------
                                                        -RCRA-    -TSCA-
  Ingredient                                 CERCLA     261.33     8(d) 
  -----------------------------------------  ------     ------    ------
  Tetrabutylammonium Hydroxide               No         No         No        
  (2052-49-5)
  Methyl Alcohol (67-56-1)                   5000       U154       No   
 
 
Chemical Weapons Convention:  No     TSCA 12(b):  No     CDTA:  No
SARA 311/312:  Acute: Yes      Chronic: Yes  Fire: Yes Pressure: No
Reactivity: No          (Mixture / Liquid)


Australian Hazchem Code: None allocated.
Poison Schedule: S6
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.

16. Other Information

NFPA Ratings: Health: 3 Flammability: 3 Reactivity: 0
Label Hazard Warning:
POISON! DANGER! CORROSIVE. CAUSES BURNS TO SKIN AND EYES. VAPOR HARMFUL. MAY BE FATAL OR CAUSE BLINDNESS IF SWALLOWED. HARMFUL IF INHALED OR ABSORBED THROUGH SKIN. CANNOT BE MADE NONPOISONOUS. FLAMMABLE LIQUID AND VAPOR. AFFECTS THE CENTRAL NERVOUS SYSTEM, GASTROINTESTINAL TRACT AND LIVER.
Label Precautions:
Do not get in eyes, on skin, or on clothing.
Do not breathe vapor or mist.
Keep container closed.
Use only with adequate ventilation.
Wash thoroughly after handling.
Keep away from heat, sparks and flame.
Label First Aid:
In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. If swallowed, induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. In all cases get medical attention immediately.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(s) changed since last revision of document include: 3.
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Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)