MSDS Number: Q4500 * * * * * Effective Date: 11/12/03 * * * * * Supercedes: 11/02/01 Quinine Monohydrochloride, Dihydrate

Quinine Monohydrochloride, Dihydrate

1. Product Identification

Synonyms: Quinine Hydrochloride, Dihydrate; Quinine Chloride, Dihydrate
CAS No.: 130-89-2 (Anhydrous); 6119-47-7 (Dihydrate)
Molecular Weight: 396.92
Chemical Formula: C20H24N2O2.HCl . 2H2O
Product Codes: 3355

2. Composition/Information on Ingredients

  Ingredient                                CAS No         Percent        Hazardous                                  
  ---------------------------------------   ------------   ------------   ---------   
  Quinine Monohydrochloride                 130-89-2         90 - 100%       Yes                                                                    

3. Hazards Identification

Emergency Overview

J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
Health Rating: 2 - Moderate
Flammability Rating: 1 - Slight
Reactivity Rating: 0 - None
Contact Rating: 1 - Slight
Lab Protective Equip: GOGGLES; LAB COAT
Storage Color Code: Orange (General Storage)

Potential Health Effects

May cause Sensitization
Is harmful
Skin Contact:
Skin sensitization.
Eye Contact:
None identified.
Chronic Exposure:
No information found.
Aggravation of Pre-existing Conditions:
No information found.

4. First Aid Measures

If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Prompt action is essential.
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact:
In case of contact, immediately wash skin with plenty of soap and water for at least 15 minutes.
Eye Contact:
In case of eye contact, immediately flush with plenty of water for at least 15 minutes.

5. Fire Fighting Measures

Not expected to be a fire hazard.
None identified.
Fire Extinguishing Media:
Water, dry chemical, foam or carbon dioxide.
Special Information:
Firefighters should wear proper protective equipment and self-contained breathing apparatus with full facepiece operated in positive pressure mode.

6. Accidental Release Measures

Wear self-contained breathing apparatus and full protective clothing. With clean shovel, carefully place material into clean, dry container and cover; remove from area. Flush spill area with water.

7. Handling and Storage

Keep container tightly closed. Suitable for any general chemical storage area. Keep product out of light. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits:
None established.
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
For conditions of use where exposure to the substance is apparent and engineering controls are not feasble, consult an industrial hygienist. For emergencies, or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection:
No information found.
Eye Protection:
Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.

9. Physical and Chemical Properties

White silky powder
No information found.
Moderate (1-10%)
Specific Gravity:
No information found.
6.5 (1% solution)
% Volatiles by volume @ 21C (70F):
Boiling Point:
No information found.
Melting Point:
115C (239F)
Vapor Density (Air=1):
Not applicable.
Vapor Pressure (mm Hg):
Not applicable.
Evaporation Rate (BuAc=1):
No information found.

10. Stability and Reactivity

Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Hydrogen chloride, oxides of nitrogen, carbon monoxide, carbon dioxide.
Hazardous Polymerization:
Will not occur.
Strong oxidizing agents, alkalis, carbonates, strong bases, iodides, tannic acid.
Conditions to Avoid:
Sunlight, ultraviolet light.

11. Toxicological Information

  --------\Cancer Lists\------------------------------------------------------
                                         ---NTP Carcinogen---
  Ingredient                             Known    Anticipated    IARC Category
  ------------------------------------   -----    -----------    -------------
  Quinine Monohydrochloride               No          No            None

12. Ecological Information

Environmental Fate:
No information found.
Environmental Toxicity:
No information found.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.

14. Transport Information

Not regulated.

15. Regulatory Information

  --------\Chemical Inventory Status - Part 1\---------------------------------
  Ingredient                                       TSCA  EC   Japan  Australia
  -----------------------------------------------  ----  ---  -----  ---------
  Quinine Monohydrochloride (130-89-2)              Yes  Yes   No       Yes                                      
  --------\Chemical Inventory Status - Part 2\---------------------------------
  Ingredient                                       Korea  DSL   NDSL  Phil.
  -----------------------------------------------  -----  ---   ----  -----
  Quinine Monohydrochloride (130-89-2)              No    Yes   No     Yes                 
  --------\Federal, State & International Regulations - Part 1\----------------
                                             -SARA 302-    ------SARA 313------
  Ingredient                                 RQ    TPQ     List  Chemical Catg.
  -----------------------------------------  ---   -----   ----  --------------
  Quinine Monohydrochloride (130-89-2)       No    No      No         No
  --------\Federal, State & International Regulations - Part 2\----------------
                                                        -RCRA-    -TSCA-
  Ingredient                                 CERCLA     261.33     8(d) 
  -----------------------------------------  ------     ------    ------
  Quinine Monohydrochloride (130-89-2)       No         No         No               
Chemical Weapons Convention:  No     TSCA 12(b):  No     CDTA:  No
SARA 311/312:  Acute: No       Chronic: No   Fire: No  Pressure: No
Reactivity: No          (Pure / Solid) 

Australian Hazchem Code: None allocated.
Poison Schedule: None allocated.
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.

16. Other Information

Label Hazard Warning:
Label Precautions:
Avoid contact with eyes, skin, clothing.
Keep in tightly closed container. Wash thoroughly after handling.
Label First Aid:
If swallowed, induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(s) changed since last revision of document include: 1.
Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)